© 2002 by Oxford University Press
Journal of the National Cancer Institute, Vol. 94, No. 16, 1183,
August 21, 2002
© 2002 Oxford University Press
Press Release
Risk from Breast Cancer Susceptibility Gene May be Exaggerated in Most Studies
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| The first 10% of the full text of this article appears below. |
An analysis of past studies on mutations in the breast cancer susceptibility genes BRCA1 and BRCA2 suggests that estimates of penetrance (or the likelihood that mutation carriers will develop breast cancer during their lifetime) have been exaggerated. This can happen because a womans risk of developing breast cancer is likely to be associated not only with the