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JNCI Journal of the National Cancer Institute 2002 94(15):1113-1114; doi:10.1093/jnci/94.15.1113
© 2002 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 94, No. 15, 1113-1114, August 7, 2002
© 2002 Oxford University Press


EDITORIAL

Stromal Therapy: The Next Step in Ovarian Cancer Treatment

Lance A. Liotta, Elise C. Kohn

Affiliation of authors: Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.

Correspondence to: Lance A. Liotta, M.D., Ph.D., Laboratory of Pathology, Center for Cancer Research, Bldg. 10, Rm. 2A33, 9000 Rockville Pike, Bethesda, MD 20892 (e-mail: liottal@mail.nih.gov).

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Among gynecologic cancers, ovarian cancer is the leading cause of death in the United States. Unfortunately, over two thirds of ovarian cancer cases are diagnosed at a late stage, when peritoneal dissemination of the ovarian cancer cells has already taken place (1). Understanding the molecular events that support the survival and implantation of disseminated ovarian cancer cells can provide urgently needed strategies for early detection, prevention, and intervention. It has long been suspected that cancer is a product of the tumor–host microenvironment . . . [Full Text of this Article]


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