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JNCI Journal of the National Cancer Institute 2002 94(14):1039; doi:10.1093/jnci/94.14.1039-b
© 2002 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 94, No. 14, 1039, July 17, 2002
© 2002 Oxford University Press


IN THIS ISSUE

The first 10% of the full text of this article appears below.

Adjuvant Therapy in Postmenopausal Women

Whether postmenopausal women with lymph node-negative breast cancer should be given adjuvant chemotherapy is controversial. The International Breast Cancer Study Group (IBCSG) (p. 1054) launched a randomized trial to evaluate the role of adjuvant chemotherapy followed by tamoxifen compared with tamoxifen alone in 1669 postmenopausal women with lymph node-negative disease. The IBCSG found that the benefit of chemotherapy was statistically significantly dependent on the estrogen receptor (ER) status of the tumor. They found that patients with ER-negative tumors had substantially better survival with chemotherapy followed by tamoxifen than with tamoxifen . . . [Full Text of this Article]

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