© 2002 by Oxford University Press
Journal of the National Cancer Institute, Vol. 94, No. 14, 1039,
July 17, 2002
© 2002 Oxford University Press
IN THIS ISSUE |
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Adjuvant Therapy in Postmenopausal Women
Whether postmenopausal women with lymph node-negative breast cancer should be given adjuvant chemotherapy is controversial. The International Breast Cancer Study Group (IBCSG) (p. 1054) launched a randomized trial to evaluate the role of adjuvant chemotherapy followed by tamoxifen compared with tamoxifen alone in 1669 postmenopausal women with lymph node-negative disease. The IBCSG found that the benefit of chemotherapy was statistically significantly dependent on the estrogen receptor (ER) status of the tumor. They found that patients with ER-negative tumors had substantially better survival with chemotherapy followed by tamoxifen than with tamoxifen
Death and Cancer-Directed Surgeries
New Diagnostic Marker for Bladder Cancer
Glucose Transporter 1 and Matrix Metalloproteinase 2
DNA Repair and Non-Small Cell Lung Cancer
Insulin-Like Growth Factor I Pathway and Prostate Cancer