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JNCI Journal of the National Cancer Institute 2002 94(12):872-873; doi:10.1093/jnci/94.12.872
© 2002 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 94, No. 12, 872-873, June 19, 2002
© 2002 Oxford University Press

EDITORIAL

Genetic Epidemiology of Melanoma: of Consortia and Conundrums

Gloria M. Petersen, Celine M. Vachon

Affiliation of authors: Department of Health Sciences Research and Mayo Clinic Cancer Center, Mayo Clinic, Rochester, MN.

Correspondence to: Gloria M. Petersen, Ph.D., Mayo Clinic, 200 First St. SW, Rochester, MN 55905 (e-mail: peterg@mayo.edu).

With the explosion of hereditary cancer gene discoveries in the last decade, investigators have been presented with a variety of avenues by which to investigate the mechanisms and implications of genetic mutations. Genetic epidemiology, which has as its objective the elucidation of genetic and nongenetic contributions to disease, has risen to the challenge. Although now considered an established field of inquiry, genetic epidemiology continues to use the tools of genetics and epidemiology, reinterpreting their concepts in the context of novel analyses. In this issue, Bishop et al. (1) report the results of a study that estimates the penetrance of CDKN2A mutations using the resources of an international melanoma . . . [Full Text of this Article]

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