© 2002 by Oxford University Press
Journal of the National Cancer Institute, Vol. 94, No. 1, 15-16,
January 2, 2002
© 2002 Oxford University Press
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Is There Less Resistance on the Chemoresistance Front?
Since the 1960s, oncologists have known that chemotherapy can cause DNA damage, second cancers, and other serious complications. The increasing popularity of multidrug regimens may increase the possibility of chemoresistance, toxicity, and a myriad of other complications.
At the November 2001 Chemotherapy Foundation meeting in New York, there was much discussion about the efficacy of doublet or triplet therapies for various cancers and the problems that administering these numbers of drugs