© 2001 by Oxford University Press
Journal of the National Cancer Institute, Vol. 93, No. 4, 252-253,
February 21, 2001
© 2001 Oxford University Press
EDITORIAL |
Cervical Carcinoma and Human Papillomavirus: On the Road to Preventing a Major Human Cancer
Correspondence to: Harald zur Hausen, M.D., D.Sc. (Hon.), Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany (e-mail: zurhausen@dkfz-heidelberg.de).
Three papers in this issue of the Journal cover important aspects of high-risk human papillomavirus (HPV) infections: the infection as an indicator of high-risk lesions (1), strain variation as an indicator for a high risk of disease progression (2), and a phase I clinical trial revealing the potent immunogenicity of the three vaccine preparations tested (3).
The question of HPV identification as a screening tool in comparison to conventional cytology resulted in controversial discussions for quite some time. The article by Solomon et al. (1) reveals that the Hybrid Capture 2TM test for HPV detection has a
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