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JNCI Journal of the National Cancer Institute 2001 93(20):1572; doi:10.1093/jnci/93.20.1572
© 2001 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 93, No. 20, 1572, October 17, 2001
© 2001 Oxford University Press

CORRESPONDENCE

Breast Cancer Screening for Women Aged 40–49 Years: Screening May Not Be the Benign Process Usually Thought

Michael Retsky, Romano Demicheli, William Hrushesky

Affiliations of authors: M. Retsky, Department of Surgery, Children's Hospital and Harvard Medical School, Boston, MA; R. Demicheli, Milan National Cancer Institute, Italy; W. Hrushesky, Dorn Veterans Affairs Medical Center, Columbia, SC.

Correspondence to: Michael Retsky, Ph.D., Children's Hospital and Harvard Medical School, Enders Bldg., 10th Floor, 300 Longwood Ave., Boston, MA 02115 (e-mail: retsky@jimmy.harvard.edu).

As reported by eight randomized trials of breast cancer screening conducted over the past 40 years, women aged 50–59 years who are screened for breast cancer have a 20%–30% survival advantage compared with unscreened control subjects. However, when women aged 40–49 years are screened, there is either no advantage or a small disadvantage to the screened population for the first 6–8 years of the trials. After that, an advantage to . . . [Full Text of this Article]

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