© 2001 by Oxford University Press
Journal of the National Cancer Institute, Vol. 93, No. 1, 13-15,
January 3, 2001
© 2001 Oxford University Press
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Scientists Recall Progress and Promise of Translational Research
In the past 50 years, there has been major growth in biomedical knowledge. But there has been a gap between the findings from the laboratory bench and their application to the patient.
One of the pioneers in bridging this gap is Thomas A. Waldmann, M.D., chief of the Metabolism Branch at the National Cancer Institute. Noting what he describes as the "bewilderingly rapid progress in biomedical research," Waldmann recalls that when he was in medical school in the 1950s, the immune system was largely a closed book. The function of the lymphocyte was unknown as was the difference between T and B cells, retroviruses had not been discovered, receptors for cells had not been discovered. But today "questions that could not even be
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