© 2000 by Oxford University Press
Journal of the National Cancer Institute, Vol. 92, No. 9, 674-675,
May 3, 2000
© 2000 Oxford University Press
EDITORIALS |
Confirmation of the "Old" Standard of Care for Ovarian Cancer and a Challenge
Correspondence to: William P. McGuire, M.D., The Gynecologic Oncology Center, Mercy Medical Center, Baltimore, MD 21202 (e-mail: wmcguire52@ aol.com).
The article by Piccart et al. (1) in this issue of the Journal confirms the importance of paclitaxel in the initial treatment of advanced ovarian cancer in a more heterogeneous group of patients (i.e., patients with stage IIB, IIC, III, or IV disease; 35% low-volume disease) than in the previously reported Gynecologic Oncology Group (GOG) trial (patients with stage IIIC or IV disease; 0% low-volume disease) (2). Perhaps, of more importance, it teaches us some important lessons about the politics of clinical trials. As Piccart et al. pointed out, this trial was designed, initiated, and completed in a short time period (<2 years)
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