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JNCI Journal of the National Cancer Institute 2000 92(6):437; doi:10.1093/jnci/92.6.437
© 2000 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 92, No. 6, 437, March 15, 2000
© 2000 Oxford University Press

IN THIS ISSUE

Cellular Retinol-Binding Protein and Breast Cancer

Cellular retinol-binding protein (CRBP) binds vitamin A and is believed to regulate its uptake and metabolism into biologically active molecules. Kuppumbatti et al. (p. 475) analyzed the expression of CRBP in normal and malignant breast tissues. They found that CRBP was expressed in all normal breast tissue specimens but was not expressed in 24% of cancerous breast tissue specimens. The lack of CRBP was as frequent in invasive lesions as it was in ductal carcinoma in situ. The authors suggest that the loss of . . . [Full Text of this Article]

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