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JNCI Journal of the National Cancer Institute 2000 92(5):357; doi:10.1093/jnci/92.5.357
© 2000 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 92, No. 5, 357, March 1, 2000
© 2000 Oxford University Press


IN THIS ISSUE

Radiation Therapy and Rectal Cancer

The conviction that postoperative radiotherapy and chemotherapy represent the standard of care for patients with Dukes’ B (stage II) and Dukes’ C (stage III) carcinoma of the rectum evolved in the absence of proper clinical trials designed to determine whether the addition of radiotherapy results in improved disease-free survival and overall survival. Wolmark et al. (p. 388) addressed this issue by conducting a randomized clinical trial (National Surgical Adjuvant Breast and Bowel Project [NSABP] Protocol R-02). Eligible patients were randomly assigned to receive postoperative adjuvant . . . [Full Text of this Article]

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