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JNCI Journal of the National Cancer Institute 2000 92(4):297-299; doi:10.1093/jnci/92.4.297
© 2000 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 92, No. 4, 297-299, February 16, 2000
© 2000 Oxford University Press

NEWS

Arthritis Drug Approved for Polyp Prevention Blazes Trail For Other Prevention Trials

Kara Smigel

Compared to the media attention surrounding the approval of tamoxifen to reduce the risk of breast cancer in high-risk women, the approval of celecoxib for the reduction of polyps in familial adenomatous polyposis (FAP) patients was a sleeper.

But the approval of celecoxib is important for two reasons: its fast-track approval based on a noncancer endpoint and its potential to prevent more than one type of cancer.

The U.S. Food and Drug Administration approved the use of celecoxib (CelebrexTM, Searle Monsanto, Skokie, Ill.) as an adjunct to usual care for patients with FAP on Dec. 23, 1999, based . . . [Full Text of this Article]


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