© 2000 by Oxford University Press
Journal of the National Cancer Institute, Vol. 92, No. 24, 1968-1969,
December 20, 2000
© 2000 Oxford University Press
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Trial Data Lacking For Elderly Patients With Breast Cancer
In November, a National Institutes of Health consensus panel evaluated which therapies are effective in preventing the spread of microscopic deposits of cancer cells after surgical removal of an early-stage breast tumor. The panel recommended that most women receive standard adjuvant treatments after surgeryradiation with hormonal therapy and/or chemotherapy.
Those largely left out of the recommendations, however, are women over 70 years old. The reason for this omission is simple: There are very few completed randomized trials with enough women age 70 or older to evaluate the relative benefits and morbidity of adjuvant therapies.
The pressing need for these data was advanced by Hyman B. Muss, M.D., associate director of the Vermont Cancer Center and one of the speakers at the consensus conference. Not only do elderly
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