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JNCI Journal of the National Cancer Institute 2000 92(21):1781-1782; doi:10.1093/jnci/92.21.1781
© 2000 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 92, No. 21, 1781-1782, November 1, 2000
© 2000 Oxford University Press

BRIEF COMMUNICATION

Report on the First Meeting of the International Collaborative Group on Hereditary Gastric Cancer

Jae-Gahb Park, Han-Kwang Yang, Woo Ho Kim, Carlos Caldas, Jun Yokota, Parry J. Guilford

Affiliations of authors: J.-G. Park, H.-K. Yang, W. H. Kim, Cancer Research Institute, Seoul National University, College of Medicine, South Korea; C. Caldas, University of Cambridge, U.K.; J. Yokota, National Cancer Center Research Institute, Tokyo, Japan; P. J. Guilford, University of Otago, New Zealand.

Correspondence to: Jae-Gahb Park, M.D., International Collaborative Group on Hereditary Gastric Cancer, c/o Cancer Research Institute, Seoul National University, College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-744, South Korea (e-mail: jgpark@plaza.snu.ac.kr).

Gastric cancer is the second leading cause of cancer death worldwide (1). Although hereditary gastric cancer is estimated to account for 5%–10% of all gastric adenocarcinomas (2,3), the paucity of consistent clinical criteria available to identify families with the disease has hindered the description of its genetic heterogeneity, prevalence, natural history, and clinical expression. Moreover, the existence of two distinct histopathologic subtypes, intestinal and diffuse, adds to the complexity of definitions.

The International Collaborative Group on Hereditary Gastric Cancer (ICG-HGC) was founded in April 1999 in Seoul, South Korea, during the 3rd International Gastric Cancer Congress. The ICG-HGC was established to define the clinical criteria for hereditary gastric cancer, to develop strategies for the management of affected families, and to promote international . . . [Full Text of this Article]

MOLECULAR GENETICS OF HEREDITARY GASTRIC CANCER

CRITERIA FOR ASCERTAINMENT OF HEREDITARY GASTRIC CANCER

Broad Screen Criteria

IGCLC Screen Criteria

CLINICAL IMPLICATIONS OF GENETIC SUSCEPTIBILITY TESTING

REFERENCES


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