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JNCI Journal of the National Cancer Institute 2000 92(21):1710-1711; doi:10.1093/jnci/92.21.1710
© 2000 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 92, No. 21, 1710-1711, November 1, 2000
© 2000 Oxford University Press

NEWS

Laser Capture Microdissection Comes Into Mainstream Use

Tracy Webb

Pathologists recognize subtle changes in tissue and cellular organization. But their qualitative impressions can sometimes yield different assessments. "One pathologist’s moderately differentiated cell is somebody else’s mild and somebody else’s severe," said James Resau, Ph.D., from the Van Andel Research Institute, Grand Rapids, Mich. "So as we get into a global diagnosis, and a global grouping of cases, what we are lacking are objective, measurable, reproducible standards that are not qualitative."

But one relatively new technology—laser capture microdissection—has come on the scene and has narrowed the window of interpretation. LCM’s ability to readily obtain and identify normal or cancerous cells has made it . . . [Full Text of this Article]

Birth of LCM

Putting LCM to Use


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