© 2000 by Oxford University Press
Journal of the National Cancer Institute, Vol. 92, No. 19, 1555,
October 4, 2000
© 2000 Oxford University Press
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How Does a Drug Get to Phase III Trials?
NCIs Drug Development Group (DDG; which replaced the Decision Network Committee in January 2000) handles most decisions on whether to continue moving investigational agents along the pipeline from preclinical testing to Investigational New Drug application filing to phase I trials. DDG is co-chaired by the associate