© 2000 by Oxford University Press
Journal of the National Cancer Institute, Vol. 92, No. 17, 1371-1373,
September 6, 2000
© 2000 Oxford University Press
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One Gene, Two Genes, Three Genes, Four: Scientists Wonder How Many More
When you were a kid, did you ever try to win a prize by guessing how many jelly beans were in the big jar? Is it 500? 5,000? Hard to tell when the numbers get so high.
If you have played this kind of guessing game, the Cold Spring Harbor (N.Y.) Laboratorys Genesweep will probably seem familiar. But instead of a pile of candy, the guesses aim at a basic question about the foundations of human life: How many genes make up the human genome?
The contest was organized by Ewan Birney, Ph.D., of the European Bioinformatics Institute in Cambridge, England, at CSHLs genome conference in May, where the topic reportedly was "hotly debated."
Now that the genomes 3 billion DNA base pairs have