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JNCI Journal of the National Cancer Institute 2000 92(17):1367-1369; doi:10.1093/jnci/92.17.1367
© 2000 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 92, No. 17, 1367-1369, September 6, 2000
© 2000 Oxford University Press

EDITORIAL

Apoptosis: Translating Theory to Therapy for Prostate Cancer

John T. Isaacs

Affiliations of author: Division of Experimental Therapeutics, The Johns Hopkins Oncology Center, and Department of Urology, The Johns Hopkins School of Medicine, Baltimore, MD.

Correspondence to: John T. Isaacs, Ph.D., Division of Experimental Therapeutics, The Johns Hopkins Oncology Center, Bunting-Blaustein Bldg., 1M44, 1650 Orleans St., Baltimore, MD 21231-1001.

Lance Armstrong's recent success as an athlete and as a cancer survivor has documented vividly that, by the appropriate focusing of mind, energy, and resources, goals can be achieved that only a few years ago appeared unrealistic. In Armstrong's case, testicular cancer that had metastasized throughout his body was eliminated by effective chemotherapy. This is not an isolated case; presently, more than 80% of men with metastatic testicular cancer are curable with aggressive therapy (1). These results clearly validate that metastatic cancer does not have to be a death sentence, if effective systemic therapy is available.

In stark contrast to these inspirational results, this year 34 000 men will die in the United States of metastatic prostate cancer despite the use of androgen ablation therapy (2). . . [Full Text of this Article]

NOTES

REFERENCES


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