© 2000 by Oxford University Press
Journal of the National Cancer Institute, Vol. 92, No. 16, 1285,
August 16, 2000
© 2000 Oxford University Press
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Leading Centers for Low-Dose Bone Marrow Transplants
Fred Hutchinson Cancer Research Center, Seattle Seattle transplanters developed the original mini transplant regimen based on years of dog experiments. They deleted up-front chemotherapy, relying instead on low doses of total body irradiation to immunosuppress the patient. Later, they began adding the anti-leukemia and