© 2000 by Oxford University Press
Journal of the National Cancer Institute, Vol. 92, No. 14, 1118-1120,
July 19, 2000
© 2000 Oxford University Press
NEWS |
Nonhormonal Agents Show Promise Against Hot Flashes
Breast cancer survivors who experience debilitating hot flashes now have a new remedy: venlafaxine (Effexor), a drug used as an antidepressant. Charles Loprinzi, M.D., of the Mayo Clinic Cancer Center in Rochester, Minn., presented his results in May at the annual meeting of the American Society of Clinical Oncology, concluding that venlafaxine at 75 mg per day reduces hot flashes in breast cancer patients by approximately 60% from baseline. This 60% reduction is in a hot flash "score" that accounts for both the frequency and severity of hot flashes.
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The 75 mg dose gave the best ratio of benefits
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