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JNCI Journal of the National Cancer Institute 2000 92(13):1092-1093; doi:10.1093/jnci/92.13.1092
© 2000 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 92, No. 13, 1092-1093, July 5, 2000
© 2000 Oxford University Press

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Breast Cancer Screening Using Small-Angle X-ray Scattering Analysis of Human Hair

Peter Meyer, Richard Goergl, Juergen Wilhelm Botz, Peter Fratzl

Affiliations of authors: P. Meyer, J. W. Botz, Institut für Humangenetik, Universitaetsklinikum Heidelberg, Germany; R. Goergl, Anton Paar GmbH, Graz, Austria, and Erich-Schmid-Institut, Leoben, Austria; P. Fratzl, Erich-Schmid-Institut der Oesterreichischen Akademie der Wissenschaften und Institut für Metallphysik, Montanuniversitaet Leoben.

Correspondence to: Peter Meyer, M.D., Institute of Human Genetics, Outpatient Clinic, Im Neuenheimer Feld 344A, 69120 Heidelberg, Germany (e-mail: Peter_Meyer@med.uni-heidelberg.de).

In a double-blind study, James et al. (1) reported consistent distinctive changes in the x-ray diffraction patterns of pubic hair from all eight patients with breast cancer compared with those of pubic hair from four healthy women. Results obtained from samples of scalp hair were almost as clear-cut; all 15 of the patients with breast cancer but only three (19%) of 16 of the healthy women showed an aberrant finding. Samples from women with a hereditary predisposition for breast cancer because they carried a BRCA1 gene mutation also showed either a full or a partial aberrant x-ray pattern (. . . [Full Text of this Article]

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