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JNCI Journal of the National Cancer Institute 1999 91(24):2063; doi:10.1093/jnci/91.24.2063
© 1999 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 91, No. 24, 2063, December 15, 1999
© 1999 Oxford University Press

IN THIS ISSUE

Oropharyngeal Cancer Treatments

The conventional treatment for oropharyngeal cancer, radiation therapy, is not very successful. To test the ability of chemotherapy given concomitantly with radiotherapy to improve the outcome in this disease, Calais et al. (p. 2081) studied 226 patients enrolled in a randomized, phase III clinical trial. The trial compared radiotherapy alone with combined ther-apy using carboplatin and 5-fluorouracil with radiation treatment. The patients were followed for a mean of 35 months, and all patients were followed for at least 12 months. Although patients receiving both radiotherapy and chemotherapy over a period of 7 weeks exhibited a significantly . . . [Full Text of this Article]

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