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JNCI Journal of the National Cancer Institute 1999 91(23):1990-1992; doi:10.1093/jnci/91.23.1990
© 1999 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 91, No. 23, 1990-1992, December 1, 1999
© 1999 Oxford University Press

NEWS

Genetic Profiling for Cancer Surfaces Slowly in the Clinic

Nancy J. Nelson

The explosive knowledge coming out of the age of genetics is having only a quiet impact in the clinic so far. But the effort to develop molecular profiles of individual patients is moving quickly and in as little as 2 years may dramatically alter how physicians treat and diagnose cancer.

Only a handful of examples now exist where genetic information — either the expression patterns of various genes or the molecular fingerprints of single genes — helps define which tumors will grow fast and which will respond to various treatment options.

"There are very few genetic tests that have reached the level of the clinic," said Bert Vogelstein, M.D., of the Howard Hughes Medical Institute and the Johns Hopkins Medical Institutions in Baltimore, Md. "But there are many on the drawing boards."

The publication of a paper in the October 15 Science gives a glimpse into the genetics of the . . . [Full Text of this Article]

Neuroblastoma

Inherited Genetics


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