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JNCI Journal of the National Cancer Institute 1999 91(20):1703; doi:10.1093/jnci/91.20.1703
© 1999 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 91, No. 20, 1703, October 20, 1999
© 1999 Oxford University Press

IN THIS ISSUE

Kaposi's Sarcoma and Expression of Human Herpesvirus 8 Genes

Human herpesvirus 8 (HHV8) infection is associated with all forms of Kaposi's sarcoma (KS). A cluster of HHV8 genes (ORFK13-72-73 locus) may contribute to KS by encoding proteins, such as the latency-associated nuclear antigen; v-cyc-D, a viral homologue of the cellular cyclin D; and an anti-apoptotic protein, v-FLIP, which inhibits programmed cell death. Stürzl et al. (p. 1725) examined expression of these genes in tissues obtained from KS patients at different disease stages. They found that the messenger RNA encoding v-cyc-D and v-FLIP is abundantly expressed . . . [Full Text of this Article]

Human Herpesvirus 8 and Transfusions

Serum {alpha}-Tocopherol and Lung Cancer Risk

Gene Therapy in a Rabbit Model

PSA Testing in Older Men

Diet and Risk of Non-Hodgkin's Lymphoma


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