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JNCI Journal of the National Cancer Institute 1999 91(18):1584-1585; doi:10.1093/jnci/91.18.1584
© 1999 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 91, No. 18, 1584-1585, September 15, 1999
© 1999 Oxford University Press

CORRESPONDENCE

Re: Prognostic Importance of Low c-erbB2 Expression in Breast Tumors

Magali Ferrero-Poüs, Kamel Hacène, Michèle Tubiana-Hulin, Frédérique Spyratos

Affiliation of authors: Centre René Huguenin de Lutte Contre Le Cancer, Saint-Cloud, France.

Correspondence to: Frédérique Spyratos, Ph.D., Laboratoire d'Oncobiologie, Centre René Huguenin, 35 rue Dailly, 92211 Saint-Cloud, France (e-mail: spyratos@calva.net).

Numerous studies involving thousands of patients have shown that c-erbB2 abnormalities (gene amplification and protein overexpression) are associated with a poor prognosis in patients with breast cancer [reviewed in (1)]. Recently, surprising data were published by Koscielny et al. in the Journal (2) and in the report of a prospective multicenter study (3) suggesting . . . [Full Text of this Article]

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