Skip Navigation

JNCI Journal of the National Cancer Institute 1999 91(14):1182-1183; doi:10.1093/jnci/91.14.1182
© 1999 by Oxford University Press
This Article
Right arrow Full Text Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Reynolds, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Reynolds, T.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of the National Cancer Institute, Vol. 91, No. 14, 1182-1183, July 21, 1999
© 1999 Oxford University Press

NEWS

Why Randomized Surgical Oncology Trials Are So Scarce

Tom Reynolds

About half of patients with solid tumors are cured by surgery alone. And yet randomized clinical trials in surgical oncology remain scarce.

Surgical oncologists offer various explanations: the difficulty of ensuring uniformity in surgical practice; the lack of funding by the pharmaceutical industry; and in the United States, the absence, until recently, of a surgically oriented cooperative clinical trials group.

Elma K. Kranenbarg, and Cornelis J. H. van de Velde, M.D., Ph.D., of the University of Leiden in the Netherlands published an editorial in a recent Japanese Journal of Clinical Oncology on the importance of surgical trials in oncology. They make a plea for greater participation of surgeons in clinical trials, and for closer attention to surgical variables in all cancer trials.



View larger version (141K):
[in this window]
[in a new window]
  		Dr. Cornelis J. H. van de Velde

 
Unique Feature

A unique feature of surgical trials, they note, is the intrinsic . . . [Full Text of this Article]

Surgery as a Constant

Surgery as a Variable


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 NEJMHome page
P. G. Rose, S. Nerenstone, M. F. Brady, D. Clarke-Pearson, G. Olt, S. C. Rubin, D. H. Moore, J. M. Small, and the Gynecologic Oncology Group
Secondary Surgical Cytoreduction for Advanced Ovarian Carcinoma
N. Engl. J. Med., December 9, 2004; 351(24): 2489 - 2497.
[Abstract] [Full Text] [PDF]