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JNCI Journal of the National Cancer Institute 1999 91(1):1; doi:10.1093/jnci/91.1.1
© 1999 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 91, No. 1, 1, January 6, 1999
© 1999 Oxford University Press


IN THIS ISSUE

Tamoxifen Resistance and Transforming Growth Factor-ß

Breast cancers can become resistant to treatment with the drug tamoxifen. Arteaga et al. (p. 46) have performed studies to uncover mechanisms that may play a role in this resistance. By use of a tamoxifen-resistant human breast cancer cell line, LCC2, and a related tamoxifen-sensitive line, LCC1, they showed that large amounts of transforming growth factor-ß2 were secreted by the resistant line but not by the sensitive line. They also showed that the growth of LCC2 tumors in nude mice could be inhibited by treatment with tamoxifen and neutralizing antibodies against . . . [Full Text of this Article]

Telomerase: Cellular Immortality and Its Reversal

Ferrets, ß-Carotene, and Tobacco Smoke

Vinorelbine, Quality of Life, and Advanced Non-Small-Cell Lung Cancer

Breast Cancer and Marital Stability

Predicting Sarcoma Aggressiveness


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