Journal of the National Cancer Institute Advance Access originally published online on April 28, 2009
JNCI Journal of the National Cancer Institute 2009 101(9):613; doi:10.1093/jnci/djp142
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© Oxford University Press 2009.
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Gene Alterations Are Associated with Better Response to Anthracycline-Based Chemotherapy for Breast Cancer
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Alterations in the topoisomerase II alpha (TOP2A) gene were associated with better patient outcomes following anthracycline-based therapy compared with non-anthracycline-based regimens, according to a study in the April 28 online issue of the Journal of the National Cancer Institute. The increased responsiveness is similar to what is seen in patients whose tumors carry an
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