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JNCI Journal of the National Cancer Institute 2009 101(3):127; doi:10.1093/jnci/djn503
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© Oxford University Press 2009.

IN THIS ISSUE

The first 10% of the full text of this article appears below.

Larynx Preservation Trial of Sequential vs Alternating Therapy

Induction chemotherapy followed by radiation therapy, and concomitant chemotherapy and radiation therapy both appear to be valuable alternatives to total laryngectomy in patients with advanced cancers of the larynx or hypotharynx. Lefebvre et al (p. 142) report the results of a phase III randomized trial in which these regimens were compared in patients with advanced larynx or hypotharynx cancer.

They found that larynx preservation, the progression-free interval, overall survival, and acute and late toxic effects were all similar in the two groups, including late severe edema and/or fibrosis among patients in both arms and grade . . . [Full Text of this Article]

HPV 18 DNA and Diagnosis of Cervical Intraepithelial Neoplasia

Germ-line Mutation in Goiter and Thyroid Carcinoma

Radiation Risk of Mammography in BRCA Mutation Carriers

STAT-3 in Anti-tumor Effects of Vegetable Compound

Conserved Mutation Confers Resistance to Imatinib


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