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Journal of the National Cancer Institute Advance Access originally published online on October 14, 2009
JNCI Journal of the National Cancer Institute 2009 101(21):1438-1439; doi:10.1093/jnci/djp397
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© Oxford University Press 2009.

NEWS

UPDATE

High-Throughput Screening Finds Potential Killer of Cancer Stem Cells

Karen Rowan

The first 10% of the full text of this article appears below.

The search for agents that target and kill cancer stem cells is on. In August, researchers reported in Cell that high-throughput screening could be used to identify drugs that target these cells, notorious for their resistance to existing treatments and their putative ability to generate new tumors.

Killing cancer stem cells may be the key to preventing cancer's recurrence, say researchers who have confidence in the cancer stem cell model of carcinogenesis. The model holds that only a specific subset of cancer cells can give rise to new cells or metastases, and some say this explains why cancers can seem to disappear after treatment and . . . [Full Text of this Article]

Clever or Too Simple?


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