© Oxford University Press 2009.
IN THIS ISSUE
| The first 10% of the full text of this article appears below. |
Multitype L2 Fusion Protein Vaccines for HPV
Current vaccines for human papillomavirus (HPV) are based on viral capsid L1 proteins and are HPV type-restricted. To determine whether L2 capsid proteins, which induce antibodies that neutralize several HPV types, would be good candidates for broad spectrum HPV vaccines, Jagu et al. (p. 782) vaccinated mice and rabbits with various HPV-16 L2 polypeptides and fusion proteins comprising L2 protective epitopes derived from several medically relevant HPV genotypes in various adjuvants or with a negative control. Both mice and rabbits vaccinated with concatenated multitype L2 fusion protein vaccines generated neutralizing antibody responses
The Role of CIP2A and MYC in Gastric Cancer
Risks of Second Cancers in Survivors of Pediatric Cancer
Diagnostic Interpretive Variability Among Mammography Facilities
RasGAP-Derived Peptide and Tumor Growth in Mice