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JNCI Journal of the National Cancer Institute 2008 100(8):519; doi:10.1093/jnci/djn116
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© Oxford University Press 2008.

IN THIS ISSUE

The first 10% of the full text of this article appears below.

High-dose Chemotherapy for Small Cell Lung Cancer

Small cell lung cancers often become resistant to chemotherapy and recur. To determine whether increasing the dose intensity of treatment with ifosfamide, carboplatin, and etoposide (ICE) would improve survival outcomes of patients with small cell lung cancer, Leyvraz et al. (p. 533) performed a randomized phase III clinical trial in which they compared 3-year survival rates of patients who were treated with high-dose (High-ICE, n = 69) vs standard-dose (Std-ICE, n = 71) therapy and the subsequent toxic effects of treatment. The median relative intensity of the treatment dose in the High-ICE arm was almost three times that in the . . . [Full Text of this Article]

Conjugated Equine Estrogen and Risk of Benign Breast Disease

Neoadjuvant Chemotherapy Strategies in Early Breast Cancer

Risk of Cancer in Blood Donors: Donation Frequency and Iron Loss

Synergistic Cytoxicity of Retinoid and Bcl-2 Inhibitor in Leukemia


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