Journal of the National Cancer Institute Advance Access originally published online on March 11, 2008
JNCI Journal of the National Cancer Institute 2008 100(6):386-387; doi:10.1093/jnci/djn069
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© Oxford University Press 2008.
NEWS |
Dietary Intervention Trial Reports No Effect on Survival After Breast Cancer
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Most of the 2.4 million breast cancer survivors are highly motivated to make healthy changes to their diets to improve their chances of survival, studies have shown. This willingness makes them an eager audience for the results of the Woman's Healthy Eating and Living (WHEL) trial, a phase III dietary intervention trial involving breast cancer survivors.
The WHEL investigators examined whether eating less fat and more vegetables, fruits, and fiber could improve survival among women diagnosed with early-stage breast cancer. The answer, published in the Journal of the American Medical Association last July, was a resounding no.
On the surface, these results contradict those of several hundred dietary prevention studies, although only a few of these involved breast cancer survivors. A closer look, however, reveals a more complex picture, which makes researchers hesitant to discount dietary recommendations altogether. Instead,
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