Journal of the National Cancer Institute Advance Access originally published online on July 8, 2008
JNCI Journal of the National Cancer Institute 2008 100(14):983-987; doi:10.1093/jnci/djn248
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© Oxford University Press 2008.
NEWS |
CSI: BIOINFORMATICS
Forensic Bioinformatician Aims To Solve Mysteries of Biomarker Studies
| The first 10% of the full text of this article appears below. |
Keith Baggerly, Ph.D., is not a detective in the traditional sense—he doesnt solve mysteries or fight crime. But his job does involve digging through data to get to the truth. Instead of reconstructing crime scenes, Baggerly spends part of his time reconstructing scientific analyses, a new field that many call forensic bioinformatics.
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In recent years, the new "-omics" sciences, including proteomics and genomics, have excited researchers with their potential for revealing the secrets of cancer. Yet they have also brought a new level of complexity to the cancer field, and with it concerns about validation and reproducibility. And that's where Baggerly comes in.
To correctly apply the new genomic findings to the patients at hand, the analyses that produced