© 1997 by Oxford University Press
A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: meeting highlights and Bethesda guidelines
MA Rodriguez-Bigas, CR Boland, SR Hamilton, DE Henson, JR Jass, PM Khan, H Lynch, M Perucho, T Smyrk, L Sobin, and S Srivastava
| You have reached the most complete version of this article accessible without further authentication.
More complete versions are available. Link to article |
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  J. Mueller, I. Gazzoli, P. Bandipalliam, J. E. Garber, S. Syngal, and R. D. Kolodner Comprehensive Molecular Analysis of Mismatch Repair Gene Defects in Suspected Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) Cases Cancer Res., September 1, 2009; 69(17): 7053 - 7061. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. C. Green, P. S. Parfrey, M. O. Woods, and H. B. Younghusband Prediction of Lynch Syndrome in Consecutive Patients With Colorectal Cancer J Natl Cancer Inst, March 4, 2009; 101(5): 331 - 340. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Bapat, N. M. Lindor, J. Baron, K. Siegmund, L. Li, Y. Zheng, R. Haile, S. Gallinger, J. R. Jass, J. P. Young, et al. The Association of Tumor Microsatellite Instability Phenotype with Family History of Colorectal Cancer Cancer Epidemiol. Biomarkers Prev., March 1, 2009; 18(3): 967 - 975. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Botteri, S. Iodice, V. Bagnardi, S. Raimondi, A. B. Lowenfels, and P. Maisonneuve Smoking and Colorectal Cancer: A Meta-analysis JAMA, December 17, 2008; 300(23): 2765 - 2778. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Hampel, W. L. Frankel, E. Martin, M. Arnold, K. Khanduja, P. Kuebler, M. Clendenning, K. Sotamaa, T. Prior, J. A. Westman, et al. Feasibility of Screening for Lynch Syndrome Among Patients With Colorectal Cancer J. Clin. Oncol., December 10, 2008; 26(35): 5783 - 5788. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Pande, C. I. Amos, D. R. Osterwisch, J. Chen, P. M. Lynch, R. Broaddus, and M. L. Frazier Genetic Variation in Genes for the Xenobiotic-Metabolizing Enzymes CYP1A1, EPHX1, GSTM1, GSTT1, and GSTP1 and Susceptibility to Colorectal Cancer in Lynch Syndrome Cancer Epidemiol. Biomarkers Prev., September 1, 2008; 17(9): 2393 - 2401. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Zhang Immunohistochemistry versus Microsatellite Instability Testing for Screening Colorectal Cancer Patients at Risk for Hereditary Nonpolyposis Colorectal Cancer Syndrome: Part II. The Utility of Microsatellite Instability Testing J. Mol. Diagn., July 1, 2008; 10(4): 301 - 307. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Imai and H. Yamamoto Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics Carcinogenesis, April 1, 2008; 29(4): 673 - 680. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. D. Walsh, M. C. Cummings, D. D. Buchanan, W. M. Dambacher, S. Arnold, D. McKeone, R. Byrnes, M. A. Barker, B. A. Leggett, M. Gattas, et al. Molecular, Pathologic, and Clinical Features of Early-Onset Endometrial Cancer: Identifying Presumptive Lynch Syndrome Patients Clin. Cancer Res., March 15, 2008; 14(6): 1692 - 1700. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. A Devlin and P. J Morrison Inherited gynaecological cancer syndromes Obstet Gynaecol (Lond), January 1, 2008; 10(1): 9 - 15. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. D. Kauff How Should Women With Early-Onset Endometrial Cancer Be Evaluated for Lynch Syndrome? J. Clin. Oncol., November 20, 2007; 25(33): 5143 - 5146. [Full Text] [PDF]
|
|
|
|
|
|
A. Sanchez-de-Abajo, M. de la Hoya, M. van Puijenbroek, A. Tosar, J.A. Lopez-Asenjo, E. Diaz-Rubio, H. Morreau, and T. Caldes Molecular Analysis of Colorectal Cancer Tumors from Patients with Mismatch Repair Proficient Hereditary Nonpolyposis Colorectal Cancer Suggests Novel Carcinogenic Pathways Clin. Cancer Res., October 1, 2007; 13(19): 5729 - 5735. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Khilko, P. Bourne, Qi Yang, and Ping Tang Mismatch Repair Genes hMLH1 and hMSH2 May Not Play an Essential Role in Breast Carcinogenesis International Journal of Surgical Pathology, July 1, 2007; 15(3): 233 - 241. [Abstract] [PDF]
|
|
|
|
 |
|
 H F A Vasen, G Moslein, A Alonso, I Bernstein, L Bertario, I Blanco, J Burn, G Capella, C Engel, I Frayling, et al. Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer) J. Med. Genet., June 1, 2007; 44(6): 353 - 362. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Valle, J. Perea, P. Carbonell, V. Fernandez, A. M. Dotor, J. Benitez, and M. Urioste Clinicopathologic and Pedigree Differences in Amsterdam I-Positive Hereditary Nonpolyposis Colorectal Cancer Families According to Tumor Microsatellite Instability Status J. Clin. Oncol., March 1, 2007; 25(7): 781 - 786. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. T. Lynch, J. F. Lynch, and P. M. Lynch Toward a Consensus in Molecular Diagnosis of Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) J Natl Cancer Inst, February 21, 2007; 99(4): 261 - 263. [Full Text] [PDF]
|
|
|
|
 |
|
 R C Niessen, M J W Berends, Y Wu, R H Sijmons, H Hollema, M J L Ligtenberg, H E K de Walle, E G E de Vries, A Karrenbeld, C H C M Buys, et al. Identification of mismatch repair gene mutations in young patients with colorectal cancer and in patients with multiple tumours associated with hereditary non-polyposis colorectal cancer Gut, December 1, 2006; 55(12): 1781 - 1788. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. G. Guillem, W. C. Wood, J. F. Moley, A. Berchuck, B. Y. Karlan, D. G. Mutch, R. F. Gagel, J. Weitzel, M. Morrow, B. L. Weber, et al. ASCO/SSO Review of Current Role of Risk-Reducing Surgery in Common Hereditary Cancer Syndromes J. Clin. Oncol., October 1, 2006; 24(28): 4642 - 4660. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Balmana, D. H. Stockwell, E. W. Steyerberg, E. M. Stoffel, A. M. Deffenbaugh, J. E. Reid, B. Ward, T. Scholl, B. Hendrickson, J. Tazelaar, et al. Prediction of MLH1 and MSH2 mutations in Lynch syndrome. JAMA, September 27, 2006; 296(12): 1469 - 1478. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Chen, W. Wang, S. Lee, K. Nafa, J. Lee, K. Romans, P. Watson, S. B. Gruber, D. Euhus, K. W. Kinzler, et al. Prediction of germline mutations and cancer risk in the Lynch syndrome. JAMA, September 27, 2006; 296(12): 1479 - 1487. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Ford and A. S. Whittemore Predicting and preventing hereditary colorectal cancer. JAMA, September 27, 2006; 296(12): 1521 - 1523. [Full Text] [PDF]
|
|
|
|
|
|
T. Goecke, K. Schulmann, C. Engel, E. Holinski-Feder, C. Pagenstecher, H. K. Schackert, M. Kloor, E. Kunstmann, H. Vogelsang, G. Keller, et al. Genotype-Phenotype Comparison of German MLH1 and MSH2 Mutation Carriers Clinically Affected With Lynch Syndrome: A Report by the German HNPCC Consortium J. Clin. Oncol., September 10, 2006; 24(26): 4285 - 4292. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Hampel, W. Frankel, J. Panescu, J. Lockman, K. Sotamaa, D. Fix, I. Comeras, J. La Jeunesse, H. Nakagawa, J. A. Westman, et al. Screening for Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) among Endometrial Cancer Patients. Cancer Res., August 1, 2006; 66(15): 7810 - 7817. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. M.C. Hendriks, A. E. de Jong, H. Morreau, C. M.J. Tops, H. F. Vasen, J. Th. Wijnen, M. H. Breuning, and A. H.J.T. Brocker-Vriends Diagnostic Approach and Management of Lynch Syndrome (Hereditary Nonpolyposis Colorectal Carcinoma): A Guide for Clinicians CA Cancer J Clin, July 1, 2006; 56(4): 213 - 225. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Lanza, R. Gafa, A. Santini, I. Maestri, L. Guerzoni, and L. Cavazzini Immunohistochemical Test for MLH1 and MSH2 Expression Predicts Clinical Outcome in Stage II and III Colorectal Cancer Patients J. Clin. Oncol., May 20, 2006; 24(15): 2359 - 2367. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Leone, G. Cavalloni, Y. Pignochino, I. Sarotto, R. Ferraris, W. Piacibello, T. Venesio, L. Capussotti, M. Risio, and M. Aglietta Somatic mutations of epidermal growth factor receptor in bile duct and gallbladder carcinoma. Clin. Cancer Res., March 15, 2006; 12(6): 1680 - 1685. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. T. Soliman, R. R. Broaddus, K. M. Schmeler, M. S. Daniels, D. Gonzalez, B. M. Slomovitz, D. M. Gershenson, and K. H. Lu Women With Synchronous Primary Cancers of the Endometrium and Ovary: Do They Have Lynch Syndrome? J. Clin. Oncol., December 20, 2005; 23(36): 9344 - 9350. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S Kruger, A Bier, C Engel, E Mangold, C Pagenstecher, M von Knebel Doeberitz, E Holinski-Feder, G Moeslein, K Schulmann, J Plaschke, et al. The p53 codon 72 variation is associated with the age of onset of hereditary non-polyposis colorectal cancer (HNPCC) J. Med. Genet., October 1, 2005; 42(10): 769 - 773. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. C. Southey, M. A. Jenkins, L. Mead, J. Whitty, M. Trivett, A. A. Tesoriero, L. D. Smith, K. Jennings, G. Grubb, S. G. Royce, et al. Use of Molecular Tumor Characteristics to Prioritize Mismatch Repair Gene Testing in Early-Onset Colorectal Cancer J. Clin. Oncol., September 20, 2005; 23(27): 6524 - 6532. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. T. Stormorken, I. M. Bowitz-Lothe, T. Noren, E. Kure, S. Aase, J. Wijnen, J. Apold, K. Heimdal, and P. Moller Immunohistochemistry Identifies Carriers of Mismatch Repair Gene Defects Causing Hereditary Nonpolyposis Colorectal Cancer J. Clin. Oncol., July 20, 2005; 23(21): 4705 - 4712. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Macrae and M. Harris Re: Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite Instability J Natl Cancer Inst, June 15, 2005; 97(12): 936 - 937. [Full Text] [PDF]
|
|
|
|
 |
|
 H. Hampel, W. L. Frankel, E. Martin, M. Arnold, K. Khanduja, P. Kuebler, H. Nakagawa, K. Sotamaa, T. W. Prior, J. Westman, et al. Screening for the Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) N. Engl. J. Med., May 5, 2005; 352(18): 1851 - 1860. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Pinol, A. Castells, M. Andreu, S. Castellvi-Bel, C. Alenda, X. Llor, R. M. Xicola, F. Rodriguez-Moranta, A. Paya, R. Jover, et al. Accuracy of Revised Bethesda Guidelines, Microsatellite Instability, and Immunohistochemistry for the Identification of Patients With Hereditary Nonpolyposis Colorectal Cancer JAMA, April 27, 2005; 293(16): 1986 - 1994. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. F. A. Vasen and C. R. Boland Progress in Genetic Testing, Classification, and Identification of Lynch Syndrome JAMA, April 27, 2005; 293(16): 2028 - 2030. [Full Text] [PDF]
|
|
|
|
|
|
J. E. Garber and K. Offit Hereditary Cancer Predisposition Syndromes J. Clin. Oncol., January 10, 2005; 23(2): 276 - 292. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L.R. Lipton, V. Johnson, C. Cummings, S. Fisher, P. Risby, A.T. Eftekhar Sadat, T. Cranston, L. Izatt, P. Sasieni, S.V. Hodgson, et al. Refining the Amsterdam Criteria and Bethesda Guidelines: Testing Algorithms for the Prediction of Mismatch Repair Mutation Status in the Familial Cancer Clinic J. Clin. Oncol., December 15, 2004; 22(24): 4934 - 4943. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Plaschke, C. Engel, S. Kruger, E. Holinski-Feder, C. Pagenstecher, E. Mangold, G. Moeslein, K. Schulmann, J. Gebert, M. von Knebel Doeberitz, et al. Lower Incidence of Colorectal Cancer and Later Age of Disease Onset in 27 Families With Pathogenic MSH6 Germline Mutations Compared With Families With MLH1 or MSH2 Mutations: The German Hereditary Nonpolyposis Colorectal Cancer Consortium J. Clin. Oncol., November 15, 2004; 22(22): 4486 - 4494. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Yuan, Y.-q. Huang, S.-r. Cai, Y.-m. Song, S. Zheng, and S.-z. Zhang Genetic Characterization of Chinese Hereditary Non-polyposis Colorectal Cancer by DHPLC and Multiplex PCR Jpn. J. Clin. Oncol., November 1, 2004; 34(11): 660 - 666. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. H. Halbert, H. Lynch, J. Lynch, D. Main, S. Kucharski, A. K. Rustgi, and C. Lerman Colon Cancer Screening Practices Following Genetic Testing for Hereditary Nonpolyposis Colon Cancer (HNPCC) Mutations Arch Intern Med, September 27, 2004; 164(17): 1881 - 1887. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E Domingo, P Laiho, M Ollikainen, M Pinto, L Wang, A J French, J Westra, T Frebourg, E Espin, M Armengol, et al. BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing J. Med. Genet., September 1, 2004; 41(9): 664 - 668. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E Mangold, C Pagenstecher, M Leister, M Mathiak, A Rutten, W Friedl, P Propping, T Ruzicka, and R Kruse A genotype-phenotype correlation in HNPCC: strong predominance of msh2 mutations in 41 patients with Muir-Torre syndrome J. Med. Genet., July 1, 2004; 41(7): 567 - 572. [Full Text] [PDF]
|
|
|
|
|
|
E. Fernandez, S. Gallus, C. La Vecchia, R. Talamini, E. Negri, and S. Franceschi Family History and Environmental Risk Factors for Colon Cancer Cancer Epidemiol. Biomarkers Prev., April 1, 2004; 13(4): 658 - 661. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. L. Bermejo, F. L. Buchner, and K. Hemminki Familial risk of endometrial cancer after exclusion of families that fulfilled Amsterdam, Japanese or Bethesda criteria for HNPCC Ann. Onc., April 1, 2004; 15(4): 598 - 604. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Umar, C. R. Boland, J. P. Terdiman, S. Syngal, A. d. l. Chapelle, J. Ruschoff, R. Fishel, N. M. Lindor, L. J. Burgart, R. Hamelin, et al. Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite Instability J Natl Cancer Inst, February 18, 2004; 96(4): 261 - 268. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Plaschke, S. Kruger, B. Jeske, F. Theissig, F. R. Kreuz, S. Pistorius, H. D. Saeger, I. Iaccarino, G. Marra, and H. K. Schackert Loss of MSH3 Protein Expression Is Frequent in MLH1-Deficient Colorectal Cancer and Is Associated with Disease Progression1 Cancer Res., February 1, 2004; 64(3): 864 - 870. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H Hampel, K Sweet, J A Westman, K Offit, and C Eng Referral for cancer genetics consultation: a review and compilation of risk assessment criteria J. Med. Genet., February 1, 2004; 41(2): 81 - 91. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J.W. Berends, Y. Wu, R. H. Sijmons, T. van der Sluis, W. B. Ek, M. J.L. Ligtenberg, N. J.W. Arts, K. A. ten Hoor, J. H. Kleibeuker, E. G.E. de Vries, et al. Toward New Strategies to Select Young Endometrial Cancer Patients for Mismatch Repair Gene Mutation Analysis J. Clin. Oncol., December 1, 2003; 21(23): 4364 - 4370. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Renkonen, Y. Zhang, H. Lohi, R. Salovaara, W. M. Abdel-Rahman, M. Nilbert, K. Aittomaki, H. J. Jarvinen, J.-P. Mecklin, A. Lindblom, et al. Altered Expression of MLH1, MSH2, and MSH6 in Predisposition to Hereditary Nonpolyposis Colorectal Cancer J. Clin. Oncol., October 1, 2003; 21(19): 3629 - 3637. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J Plaschke, J Ruschoff, and H K Schackert Genomic rearrangements of hMSH6 contribute to the genetic predisposition in suspected hereditary non-polyposis colorectal cancer syndrome J. Med. Genet., August 1, 2003; 40(8): 597 - 600. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Goel, C. N. Arnold, D. Niedzwiecki, D. K. Chang, L. Ricciardiello, J. M. Carethers, J. M. Dowell, L. Wasserman, C. Compton, R. J. Mayer, et al. Characterization of Sporadic Colon Cancer by Patterns of Genomic Instability Cancer Res., April 1, 2003; 63(7): 1608 - 1614. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. C. Chung and A. K. Rustgi The Hereditary Nonpolyposis Colorectal Cancer Syndrome: Genetics and Clinical Implications Ann Intern Med, April 1, 2003; 138(7): 560 - 570. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. T. Lynch and A. de la Chapelle Hereditary Colorectal Cancer N. Engl. J. Med., March 6, 2003; 348(10): 919 - 932. [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Hendriks, P. Franken, J. W. Dierssen, W. de Leeuw, J. Wijnen, E. Dreef, C. Tops, M. Breuning, A. Brocker-Vriends, H. Vasen, et al. Conventional and Tissue Microarray Immunohistochemical Expression Analysis of Mismatch Repair in Hereditary Colorectal Tumors Am. J. Pathol., February 1, 2003; 162(2): 469 - 477. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. J. Mitchell, S. M. Farrington, M. G. Dunlop, and H. Campbell Mismatch Repair Genes hMLH1 and hMSH2 and Colorectal Cancer: A HuGE Review Am. J. Epidemiol., November 15, 2002; 156(10): 885 - 902. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M G Dunlop Guidance on gastrointestinal surveillance for hereditary non-polyposis colorectal cancer, familial adenomatous polypolis, juvenile polyposis, and Peutz-Jeghers syndrome Gut, October 1, 2002; 51(90005): v21 - 27. [Full Text] [PDF]
|
|
|
|
|
|
S. S. Wahlberg, J. Schmeits, G. Thomas, M. Loda, J. Garber, S. Syngal, R. D. Kolodner, and E. Fox Evaluation of Microsatellite Instability and Immunohistochemistry for the Prediction of Germ-Line MSH2 and MLH1 Mutations in Hereditary Nonpolyposis Colon Cancer Families Cancer Res., June 1, 2002; 62(12): 3485 - 3492. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Kariola, T. E. Raevaara, K. E. Lonnqvist, and M. Nystrom-Lahti Functional analysis of MSH6 mutations linked to kindreds with putative hereditary non-polyposis colorectal cancer syndrome Hum. Mol. Genet., May 16, 2002; 11(11): 1303 - 1310. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J Carayol, M Khlat, J Maccario, and C Bonaiti-Pellie Hereditary non-polyposis colorectal cancer: current risks of colorectal cancer largely overestimated J. Med. Genet., May 1, 2002; 39(5): 335 - 339. [Full Text] [PDF]
|
|
|
|
|
|
M. Scartozzi, F. Bianchi, S. Rosati, E. Galizia, A. Antolini, C. Loretelli, A. Piga, I. Bearzi, R. Cellerino, and E. Porfiri Mutations of hMLH1 and hMSH2 in Patients With Suspected Hereditary Nonpolyposis Colorectal Cancer: Correlation With Microsatellite Instability and Abnormalities of Mismatch Repair Protein Expression J. Clin. Oncol., March 1, 2002; 20(5): 1203 - 1208. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Muller, T. B. Edmonston, D. A. Corao, D. G. Rose, J. P. Palazzo, H. Becker, R. D. Fry, J. Rueschoff, and R. Fishel Exclusion of Breast Cancer as an Integral Tumor of Hereditary Nonpolyposis Colorectal Cancer Cancer Res., February 1, 2002; 62(4): 1014 - 1019. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. M. Sweet, T. L. Bradley, and J. A. Westman Identification and Referral of Families at High Risk for Cancer Susceptibility J. Clin. Oncol., January 15, 2002; 20(2): 528 - 537. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N Katballe, M Christensen, F P Wikman, T F Orntoft, and S Laurberg Frequency of hereditary non-polyposis colorectal cancer in Danish colorectal cancer patients Gut, January 1, 2002; 50(1): 43 - 51. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Young, L. A. Simms, K. G. Biden, C. Wynter, V. Whitehall, R. Karamatic, J. George, J. Goldblatt, I. Walpole, S.-A. Robin, et al. Features of Colorectal Cancers with High-Level Microsatellite Instability Occurring in Familial and Sporadic Settings : Parallel Pathways of Tumorigenesis Am. J. Pathol., December 1, 2001; 159(6): 2107 - 2116. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. L. Bacon, M. G. Dunlop, and S. M. Farrington Hypermutability at a poly(A/T) tract in the human germline Nucleic Acids Res., November 1, 2001; 29(21): 4405 - 4413. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Tsao Genetics of Nonmelanoma Skin Cancer Arch Dermatol, November 1, 2001; 137(11): 1486 - 1492. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Raedle, J. Trojan, A. Brieger, N. Weber, D. Schafer, G. Plotz, E. Staib-Sebler, S. Kriener, M. Lorenz, and S. Zeuzem Bethesda Guidelines: Relation to Microsatellite Instability and MLH1 Promoter Methylation in Patients with Colorectal Cancer Ann Intern Med, October 16, 2001; 135(8_Part_1): 566 - 576. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. D. Ramsey, L. Clarke, R. Etzioni, M. Higashi, K. Berry, and N. Urban Cost-Effectiveness of Microsatellite Instability Screening as a Method for Detecting Hereditary Nonpolyposis Colorectal Cancer Ann Intern Med, October 16, 2001; 135(8_Part_1): 577 - 588. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L A Clarke, C S Rebelo, J Goncalves, M G Boavida, and P Jordan PCR amplification introduces errors into mononucleotide and dinucleotide repeat sequences Mol. Pathol., October 1, 2001; 54(5): 351 - 353. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Hemminki, X. Li, and C. Dong Second Primary Cancers after Sporadic and Familial Colorectal Cancer Cancer Epidemiol. Biomarkers Prev., July 1, 2001; 10(7): 793 - 798. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. L. Wiesner, P. Platzer, S. Buxbaum, S. Lewis, M. MacMillen, J. Olechnowicz, J. Willis, A. Chakravarti, R. C. Elston, and S. D. Markowitz Testing for Colon Neoplasia Susceptibility Variants at the Human COX2 Locus J Natl Cancer Inst, April 18, 2001; 93(8): 635 - 639. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Alexander, T. Watanabe, T.-T. Wu, A. Rashid, S. Li, and S. R. Hamilton Histopathological Identification of Colon Cancer with Microsatellite Instability Am. J. Pathol., February 1, 2001; 158(2): 527 - 535. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. T. Lynch and J. Lynch Lynch Syndrome: Genetics, Natural History, Genetic Counseling, and Prevention J. Clin. Oncol., November 1, 2000; 18(90001): 19s - 31. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. L. Frazier, L.-K. Su, C. I. Amos, and P. M. Lynch Current Applications of Genetic Technology in Predisposition Testing and Microsatellite Instability Assays J. Clin. Oncol., November 1, 2000; 18(90001): 70s - 74. [Full Text] [PDF]
|
|
|
|
|
|
P. Starostik, A. Greiner, S. Schwarz, J. Patzner, A. Schultz, and H. K. Muller-Hermelink The Role of Microsatellite Instability in Gastric Low- and High-Grade Lymphoma Development Am. J. Pathol., October 1, 2000; 157(4): 1129 - 1136. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. J. Peel, A. Ziogas, E. A. Fox, M. Gildea, B. Laham, E. Clements, R. D. Kolodner, and H. Anton-Culver Characterization of Hereditary Nonpolyposis Colorectal Cancer Families From a Population-Based Series of Cases J Natl Cancer Inst, September 20, 2000; 92(18): 1517 - 1522. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Syngal, E. A Fox, C. Eng, R. D Kolodner, and J. E Garber Sensitivity and specificity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations in MSH2 and MLH1 J. Med. Genet., September 1, 2000; 37(9): 641 - 645. [Abstract] [Full Text]
|
|
|
|
|
|
H C Kim, J M D Wheeler, J C Kim, M Ilyas, N E Beck, B S Kim, K C Park, and W F Bodmer The E-cadherin gene (CDH1) variants T340A and L599V in gastric and colorectal cancer patients in Korea Gut, August 1, 2000; 47(2): 262 - 267. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J M D WHEELER, W F BODMER, and N J M. MORTENSEN DNA mismatch repair genes and colorectal cancer Gut, July 1, 2000; 47(1): 148 - 153. [Full Text] [PDF]
|
|
|
|
|
|
M. MONTERA, N. RESTA, C. SIMONE, G. GUANTI, C. MARCHESE, S. CIVITELLI, A. MANCINI, S. POZZI, L. DE SALVO, D. BRUZZONE, et al. Mutational germline analysis of hMSH2 and hMLH1 genes in early onset colorectal cancer patients J. Med. Genet., July 1, 2000; 37(7): 7e - 7. [Full Text]
|
|
|
|
|
|
S. Syngal Hereditary Nonpolyposis Colorectal Cancer: A Call for Attention J. Clin. Oncol., June 11, 2000; 18(11): 2189 - 2192. [Full Text] [PDF]
|
|
|
|
|
|
A. Chao, F. Gilliland, C. Willman, N. Joste, I-M. Chen, N. Stone, J. Ruschulte, D. Viswanatha, P. Duncan, R. Ming, et al. Patient and Tumor Characteristics of Colon Cancers with Microsatellite Instability: A Population-based Study Cancer Epidemiol. Biomarkers Prev., June 1, 2000; 9(6): 539 - 544. [Abstract] [Full Text]
|
|
|
|
|
|
M. Ponz de Leon, L. Roncucci, K. Heinimann, H. Muller, Z. Dobbie, R. Gryfe, M. Redston, and S. Gallinger Microsatellite Instability in Colorectal Cancer N. Engl. J. Med., May 25, 2000; 342(21): 1607 - 1608. [Full Text]
|
|
|
|
|
|
J. Westman, H. Hampel, and T. Bradley Efficacy of a touchscreen computer based family cancer history questionnaire and subsequent cancer risk assessment J. Med. Genet., May 1, 2000; 37(5): 354 - 360. [Abstract] [Full Text]
|
|
|
|
|
|
R. E. Wilentz, M. Goggins, M. Redston, V. A. Marcus, N. V. Adsay, T. A. Sohn, S. S. Kadkol, C. J. Yeo, M. Choti, M. Zahurak, et al. Genetic, Immunohistochemical, and Clinical Features of Medullary Carcinoma of the Pancreas : A Newly Described and Characterized Entity Am. J. Pathol., May 1, 2000; 156(5): 1641 - 1651. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Starostik, A. Greiner, A. Schultz, A. Zettl, K. Peters, A. Rosenwald, M. Kolve, and H. K. Muller-Hermelink Genetic aberrations common in gastric high-grade large B-cell lymphoma Blood, February 15, 2000; 95(4): 1180 - 1187. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. D. Berg, C. L. Glaser, R. E. Thompson, S. R. Hamilton, C. A. Griffin, and J. R. Eshleman Detection of Microsatellite Instability by Fluorescence Multiplex Polymerase Chain Reaction J. Mol. Diagn., February 1, 2000; 2(1): 20 - 28. [Abstract] [Full Text]
|
|
|
|
|
|
R. D. Kolodner, J. D. Tytell, J. L. Schmeits, M. F. Kane, R. Das Gupta, J. Weger, S. Wahlberg, E. A. Fox, D. Peel, A. Ziogas, et al. Germ-line msh6 Mutations in Colorectal Cancer Families Cancer Res., October 1, 1999; 59(20): 5068 - 5074. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Lanza, R. Gafa, M. Matteuzzi, and A. Santini Medullary-Type Poorly Differentiated Adenocarcinoma of the Large Bowel: A Distinct Clinicopathologic Entity Characterized by Microsatellite Instability and Improved Survival J. Clin. Oncol., August 1, 1999; 17(8): 2429 - 2429. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Syngal, E. A. Fox, C. Li, M. Dovidio, C. Eng, R. D. Kolodner, and J. E. Garber Interpretation of Genetic Test Results for Hereditary Nonpolyposis Colorectal Cancer: Implications for Clinical Predisposition Testing JAMA, July 21, 1999; 282(3): 247 - 253. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. L. Chan, S. T. Yuen, L. P. Chung, J. W. C. Ho, K. Y. M. Kwan, A. S. Y. Chan, J. C. Y. Ho, S. Y. Leung, and A. H. Wyllie Frequent Microsatellite Instability and Mismatch Repair Gene Mutations in Young Chinese Patients With Colorectal Cancer J Natl Cancer Inst, July 21, 1999; 91(14): 1221 - 1226. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M P. de Leon, M Pedroni, P Benatti, A Percesepe, C Di Gregorio, M Foroni, G Rossi, M Genuardi, G Neri, F Leonardi, et al. Hereditary colorectal cancer in the general population: from cancer registration to molecular diagnosis Gut, July 1, 1999; 45(1): 32 - 38. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Potter Colorectal Cancer: Molecules and Populations J Natl Cancer Inst, June 2, 1999; 91(11): 916 - 932. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Fujiwara, J. M. Stolker, T. Watanabe, A. Rashid, P. Longo, J. R. Eshleman, S. Booker, H. T. Lynch, J. R. Jass, J. S. Green, et al. Accumulated Clonal Genetic Alterations in Familial and Sporadic Colorectal Carcinomas with Widespread Instability in Microsatellite Sequences Am. J. Pathol., October 1, 1998; 153(4): 1063 - 1078. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. T. Wijnen, H. F.A. Vasen, P. M. Khan, A. H. Zwinderman, H. van der Klift, A. Mulder, C. Tops, P. Moller, R. Fodde, F. Menko, et al. Clinical Findings with Implications for Genetic Testing in Families with Clustering of Colorectal Cancer N. Engl. J. Med., August 20, 1998; 339(8): 511 - 518. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. T. Lynch and T. C. Smyrk Identifying Hereditary Nonpolyposis Colorectal Cancer N. Engl. J. Med., May 21, 1998; 338(21): 1537 - 1538. [Full Text]
|
|
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||