© 1991 by Oxford University Press
The Role of Soy Products in Reducing Risk of Cancer
Mark Messina and Stephen Barnes
| You have reached the most complete version of this article accessible without further authentication.
More complete versions are available. Link to article |
Article topics:
- Oncology..Diet and Nutrition
- Oncology..Prevention of Cancer
- Agriculture..Soybeans
- Endocrinology..Isoflavones
- Oncology..Causes and Prevention
- Medicine..Equol
- Oncology..Environmental Causes of Cancer
- Medicine..Diet
- Physiology..Humans
- Agriculture..Fruits and Vegetables
- Agriculture..Legumes
This article has been cited by other articles:
![]() |
F. Akdemir and K. Sahin Genistein supplementation to the quail: Effects on egg production and egg yolk genistein, daidzein, and lipid peroxidation levels Poult. Sci., October 1, 2009; 88(10): 2125 - 2131. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. H. Brown, S. M. Baidas, J. J. Hajdenberg, O. R. Kayaleh, G. K. Pennock, N. C. Shah, and J. E. Tseng Lifestyle Interventions in the Prevention and Treatment of Cancer American Journal of Lifestyle Medicine, September 1, 2009; 3(5): 337 - 348. [Abstract] [PDF] |
||||
![]() |
M. Messina and A. H Wu Perspectives on the soy-breast cancer relation Am. J. Clinical Nutrition, May 1, 2009; 89(5): 1673S - 1679S. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Maskarinec, M. Verheus, F. M. Steinberg, P. Amato, M. K. Cramer, R. D. Lewis, M. J. Murray, R. L. Young, and W. W. Wong Various Doses of Soy Isoflavones Do Not Modify Mammographic Density in Postmenopausal Women J. Nutr., May 1, 2009; 139(5): 981 - 986. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Messina, S. Watanabe, and K. D. R. Setchell Report on the 8th International Symposium on the Role of Soy in Health Promotion and Chronic Disease Prevention and Treatment J. Nutr., April 1, 2009; 139(4): 796S - 802S. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Dhaubhadel, M. Farhangkhoee, and R. Chapman Identification and characterization of isoflavonoid specific glycosyltransferase and malonyltransferase from soybean seeds J. Exp. Bot., March 2, 2008; (2008) ern046v2. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. J. Fuhrman, B. E. Teter, M. Barba, C. Byrne, A. Cavalleri, B. J. Grant, P. J. Horvath, D. Morelli, E. Venturelli, and P. C. Muti Equol Status Modifies the Association of Soy Intake and Mammographic Density in a Sample of Postmenopausal Women Cancer Epidemiol. Biomarkers Prev., January 1, 2008; 17(1): 33 - 42. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. Su, F. A. Simmen, R. Xiao, and R. C. M. Simmen Expression profiling of rat mammary epithelial cells reveals candidate signaling pathways in dietary protection from mammary tumors Physiol Genomics, June 19, 2007; 30(1): 8 - 16. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Cotterchio, B. A. Boucher, M. Manno, S. Gallinger, A. Okey, and P. Harper Dietary Phytoestrogen Intake Is Associated with Reduced Colorectal Cancer Risk J. Nutr., December 1, 2006; 136(12): 3046 - 3053. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Messina, W. McCaskill-Stevens, and J. W. Lampe Addressing the soy and breast cancer relationship: review, commentary, and workshop proceedings. J Natl Cancer Inst, September 20, 2006; 98(18): 1275 - 1284. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. Gallo, C. Ferlini, M. Fabrizi, S. Prislei, and G. Scambia Lack of stimulatory activity of a Phytoestrogen-containing soy extract on the growth of breast cancer tumors in mice Carcinogenesis, July 1, 2006; 27(7): 1404 - 1409. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. J. Ronis, Y. Chen, J. Badeaux, E. Laurenzana, and T. M. Badger Soy Protein Isolate Induces CYP3A1 and CYP3A2 in Prepubertal Rats Experimental Biology and Medicine, January 1, 2006; 231(1): 60 - 69. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y.-W. Chen, S.-C. Huang, S.-Y. Lin-Shiau, and J.-K. Lin Bowman-Birk inhibitor abates proteasome function and suppresses the proliferation of MCF7 breast cancer cells through accumulation of MAP kinase phosphatase-1 Carcinogenesis, July 1, 2005; 26(7): 1296 - 1306. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. H. Khan, L. Prasad, A. Sultana, and S. Sultana Soy isoflavones inhibits the genotoxicity of benzo(a)pyrene in Swiss albino mice Human and Experimental Toxicology, March 1, 2005; 24(3): 149 - 155. [Abstract] [PDF] |
||||
![]() |
B. Liu, S. Edgerton, X. Yang, A. Kim, D. Ordonez-Ercan, T. Mason, K. Alvarez, C. McKimmey, N. Liu, and A. Thor Low-Dose Dietary Phytoestrogen Abrogates Tamoxifen-Associated Mammary Tumor Prevention Cancer Res., February 1, 2005; 65(3): 879 - 886. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. Deeb, H. Jiang, X. Gao, M. S. Hafner, H. Wong, G. Divine, R. A. Chapman, S. A. Dulchavsky, and S. C. Gautam Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-{kappa}B through suppression of I{kappa}B{alpha} phosphorylation Mol. Cancer Ther., July 1, 2004; 3(7): 803 - 812. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Muti, A. B. Awad, H. Schunemann, C. S. Fink, K. Hovey, J. L. Freudenheim, Y.-W. B. Wu, C. Bellati, V. Pala, and F. Berrino A Plant Food-Based Diet Modifies the Serum {beta}-Sitosterol Concentration in Hyperandrogenic Postmenopausal Women J. Nutr., December 1, 2003; 133(12): 4252 - 4255. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Wei, R. Saladi, Y. Lu, Y. Wang, S. R. Palep, J. Moore, R. Phelps, E. Shyong, and M. G. Lebwohl Isoflavone Genistein: Photoprotection and Clinical Implications in Dermatology J. Nutr., November 1, 2003; 133(11): 3811S - 3819. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Belenky, J. Prasain, H. Kim, and S. Barnes DING, a Genistein Target in Human Breast Cancer: A Protein Without a Gene J. Nutr., July 1, 2003; 133(7): 2497S - 2501. [Abstract] [Full Text] [PDF] |
||||
![]() |
W. Miltyk, C. N Craciunescu, L. Fischer, R. A Jeffcoat, M. A Koch, W. Lopaczynski, C. Mahoney, R. A Jeffcoat, J. Crowell, J. Paglieri, et al. Lack of significant genotoxicity of purified soy isoflavones (genistein, daidzein, and glycitein) in 20 patients with prostate cancer Am. J. Clinical Nutrition, April 1, 2003; 77(4): 875 - 882. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. Deeb, Y. X. Xu, H. Jiang, X. Gao, N. Janakiraman, R. A. Chapman, and S. C. Gautam Curcumin (Diferuloyl-Methane) Enhances Tumor Necrosis Factor-related Apoptosis-inducing Ligand-induced Apoptosis in LNCaP Prostate Cancer Cells Mol. Cancer Ther., January 1, 2003; 2(1): 95 - 103. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. S. Frey and K. W. Singletary Genistein Activates p38 Mitogen-Activated Protein Kinase, Inactivates ERK1/ERK2 and Decreases Cdc25C Expression in Immortalized Human Mammary Epithelial Cells J. Nutr., January 1, 2003; 133(1): 226 - 231. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. T Bloedon, A R. Jeffcoat, W. Lopaczynski, M. J Schell, T. M Black, K. J Dix, B. F Thomas, C. Albright, M. G Busby, J. A Crowell, et al. Safety and pharmacokinetics of purified soy isoflavones: single-dose administration to postmenopausal women Am. J. Clinical Nutrition, November 1, 2002; 76(5): 1126 - 1137. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. C. Rowlands, R. Hakkak, M. J. J. Ronis, and T. M. Badger Altered Mammary Gland Differentiation and Progesterone Receptor Expression in Rats Fed Soy and Whey Proteins Toxicol. Sci., November 1, 2002; 70(1): 40 - 45. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. H. Wu, F. Z. Stanczyk, A. Seow, H.-P. Lee, and M. C. Yu Soy Intake and Other Lifestyle Determinants of Serum Estrogen Levels among Postmenopausal Chinese Women in Singapore Cancer Epidemiol. Biomarkers Prev., September 1, 2002; 11(9): 844 - 851. [Abstract] [Full Text] [PDF] |
||||
![]() |
J L Burton and M Wells The effect of phytoestrogens on the female genital tract J. Clin. Pathol., June 1, 2002; 55(6): 401 - 407. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Maskarinec, A. E. Williams, J. S. Inouye, F. Z. Stanczyk, and A. A. Franke A Randomized Isoflavone Intervention among Premenopausal Women Cancer Epidemiol. Biomarkers Prev., February 1, 2002; 11(2): 195 - 201. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. Q. Shyong, Y. Lu, A. Lazinsky, R. N. Saladi, R. G. Phelps, L. M. Austin, M. Lebwohl, and H. Wei Effects of the isoflavone 4',5,7-trihydroxyisoflavone (genistein) on psoralen plus ultraviolet A radiation (PUVA)-induced photodamage Carcinogenesis, February 1, 2002; 23(2): 317 - 321. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. J. Messina and C. L. Loprinzi Soy for Breast Cancer Survivors: A Critical Review of the Literature J. Nutr., November 1, 2001; 131(11): 3095S - 3108. [Abstract] [Full Text] [PDF] |
||||
![]() |
A. F. Galvez, N. Chen, J. Macasieb, and B. O. de Lumen Chemopreventive Property of a Soybean Peptide (Lunasin) That Binds to Deacetylated Histones and Inhibits Acetylation Cancer Res., October 1, 2001; 61(20): 7473 - 7478. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. L. Horn-Ross, E. M. John, M. Lee, S. L. Stewart, J. Koo, L. C. Sakoda, A. C. Shiau, J. Goldstein, P. Davis, and E. J. Perez-Stable Phytoestrogen Consumption and Breast Cancer Risk in a Multiethnic Population: The Bay Area Breast Cancer Study Am. J. Epidemiol., September 1, 2001; 154(5): 434 - 441. [Abstract] [Full Text] [PDF] |
||||
![]() |
W. Pan, K. Ikeda, M. Takebe, and Y. Yamori Genistein, Daidzein and Glycitein Inhibit Growth and DNA Synthesis of Aortic Smooth Muscle Cells from Stroke-Prone Spontaneously Hypertensive Rats J. Nutr., April 1, 2001; 131(4): 1154 - 1158. [Abstract] [Full Text] |
||||
![]() |
M. J. Ronis, J. C. Rowlands, R. Hakkak, and T. M. Badger Inducibility of Hepatic CYP1A Enzymes by 3-Methylcholanthrene and Isosafrole Differs in Male Rats Fed Diets Containing Casein, Soy Protein Isolate or Whey from Conception to Adulthood J. Nutr., April 1, 2001; 131(4): 1180 - 1188. [Abstract] [Full Text] |
||||
![]() |
W. B. Armstrong, A. R. Kennedy, X. S. Wan, T. H. Taylor, Q. A. Nguyen, J. Jensen, W. Thompson, W. Lagerberg, and F. L. Meyskens Jr. Clinical Modulation of Oral Leukoplakia and Protease Activity by Bowman-Birk Inhibitor Concentrate in a Phase IIa Chemoprevention Trial Clin. Cancer Res., December 1, 2000; 6(12): 4684 - 4691. [Abstract] [Full Text] |
||||
![]() |
A. B. Awad and C. S. Fink Phytosterols as Anticancer Dietary Components: Evidence and Mechanism of Action J. Nutr., September 1, 2000; 130(9): 2127 - 2130. [Abstract] [Full Text] |
||||
![]() |
L.-J. W. Lu, K. E. Anderson, J. J. Grady, F. Kohen, and M. Nagamani Decreased Ovarian Hormones during a Soya Diet: Implications for Breast Cancer Prevention Cancer Res., August 1, 2000; 60(15): 4112 - 4121. [Abstract] [Full Text] |
||||
![]() |
W. W. and C. M. Higuchi Dietary Soy Protein Is Associated with Reduced Intestinal Mucosal Polyamine Concentration in Male Wistar Rats J. Nutr., July 1, 2000; 130(7): 1815 - 1820. [Abstract] [Full Text] |
||||
![]() |
T. Ohta, S. Nakatsugi, K. Watanabe, T. Kawamori, F. Ishikawa, M. Morotomi, S. Sugie, T. Toda, T. Sugimura, and K. Wakabayashi Inhibitory effects of Bifidobacterium-fermented soy milk on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced rat mammary carcinogenesis, with a partial contribution of its component isoflavones Carcinogenesis, May 1, 2000; 21(5): 937 - 941. [Abstract] [Full Text] [PDF] |
||||
![]() |
X. Xu, H.-J. Wang, P. A. Murphy, and S. Hendrich Neither Background Diet Nor Type of Soy Food Affects Short-Term Isoflavone Bioavailability in Women J. Nutr., April 1, 2000; 130(4): 798 - 801. [Abstract] [Full Text] |
||||
![]() |
L.-J. W. Lu, M. Cree, S. Josyula, M. Nagamani, J. J. Grady, and K. E. Anderson Increased Urinary Excretion of 2-Hydroxyestrone but not 16{{alpha}}-Hydroxyestrone in Premenopausal Women during a Soya Diet Containing Isoflavones Cancer Res., March 1, 2000; 60(5): 1299 - 1305. [Abstract] [Full Text] |
||||
![]() |
F. Squadrito, D. Altavilla, G. Squadrito, A. Saitta, D. Cucinotta, L. Minutoli, B. Deodato, M. Ferlito, G. M. Campo, A. Bova, et al. Genistein supplementation and estrogen replacement therapy improve endothelial dysfunction induced by ovariectomy in rats Cardiovasc Res, January 14, 2000; 45(2): 454 - 462. [Abstract] [Full Text] [PDF] |
||||
![]() |
W. B. Armstrong, A. R. Kennedy, X. S. Wan, J. Atiba, C. E. McLaren, and F. L. Meyskens Jr. Single-Dose Administration of Bowman-Birk Inhibitor Concentrate in Patients with Oral Leukoplakia Cancer Epidemiol. Biomarkers Prev., January 1, 2000; 9(1): 43 - 47. [Abstract] [Full Text] |
||||
![]() |
S.-J. Su, T.-M. Yeh, H.-Y. Lei, and N.-H. Chow The Potential of Soybean Foods as a Chemoprevention Approach for Human Urinary Tract Cancer Clin. Cancer Res., January 1, 2000; 6(1): 230 - 236. [Abstract] [Full Text] |
||||
![]() |
M. J Ronis, J. C. Rowlands, R. Hakkak, and T. M. Badger Altered Expression and Glucocorticoid-Inducibility of Hepatic CYP3A and CYP2B Enzymes in Male Rats Fed Diets Containing Soy Protein Isolate J. Nutr., November 1, 1999; 129(11): 1958 - 1965. [Abstract] [Full Text] |
||||
![]() |
L. C. Appelt and M. M. Reicks Soy Induces Phase II Enzymes But Does Not Inhibit Dimethylbenz[a]anthracene-Induced Carcinogenesis in Female Rats J. Nutr., October 1, 1999; 129(10): 1820 - 1826. [Abstract] [Full Text] |
||||
![]() |
M. J Messina Legumes and soybeans: overview of their nutritional profiles and health effects Am. J. Clinical Nutrition, September 1, 1999; 70(3): 439S - 450. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. H Haddad, J. Sabate, and C. G Whitten Vegetarian food guide pyramid: a conceptual framework Am. J. Clinical Nutrition, September 1, 1999; 70(3): 615S - 619. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Segasothy and P.A. Phillips Vegetarian diet: panacea for modern lifestyle diseases? QJM, September 1, 1999; 92(9): 531 - 544. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. J. Davies, E. A. Bowey, H. Adlercreutz, I. R. Rowland, and P. C. Rumsby Effects of soy or rye supplementation of high-fat diets on colon tumour development in azoxymethane-treated rats Carcinogenesis, June 1, 1999; 20(6): 927 - 931. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y. Zhang, G.-J. Wang, T. T. Song, P. A. Murphy, and S. Hendrich Urinary Disposition of the Soybean Isoflavones Daidzein, Genistein and Glycitein Differs among Humans with Moderate Fecal Isoflavone Degradation Activity J. Nutr., May 1, 1999; 129(5): 957 - 962. [Abstract] [Full Text] |
||||
![]() |
C. Lopez-Otin and E. P. Diamandis Breast and Prostate Cancer: An Analysis of Common Epidemiological, Genetic, and Biochemical Features Endocr. Rev., August 1, 1998; 19(4): 365 - 396. [Abstract] [Full Text] [PDF] |
||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||



















