© 1990 by Oxford University Press
What Is the Evidence That Tumors Are Angiogenesis Dependent?
Judah Folkman
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Article topics:
- Oncology..Tumor Physiology
- Physiology..Mice
- Developmental Biology..Angiogenesis
- Physiology..Neovascularization
- Physiology..Nerves
- Oncology..Metastasis
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S.-L. Pan, J.-H. Guh, C.-Y. Peng, S.-W. Wang, Y.-L. Chang, F.-C. Cheng, J.-H. Chang, S.-C. Kuo, F.-Y. Lee, and C.-M. Teng YC-1 [3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl Indazole] Inhibits Endothelial Cell Functions Induced by Angiogenic Factors in Vitro and Angiogenesis in Vivo Models J. Pharmacol. Exp. Ther., July 1, 2005; 314(1): 35 - 42. [Abstract] [Full Text] [PDF] |
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J. J. Marler, S. J. Fishman, S. M. Kilroy, J. Fang, J. Upton, J. B. Mulliken, P. E. Burrows, D. Zurakowski, J. Folkman, and M. A. Moses Increased Expression of Urinary Matrix Metalloproteinases Parallels the Extent and Activity of Vascular Anomalies Pediatrics, July 1, 2005; 116(1): 38 - 45. [Abstract] [Full Text] [PDF] |
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P. H. Thaker, S. Yazici, M. B. Nilsson, K. Yokoi, R. Z. Tsan, J. He, S.-J. Kim, I. J. Fidler, and A. K. Sood Antivascular Therapy for Orthotopic Human Ovarian Carcinoma through Blockade of the Vascular Endothelial Growth Factor and Epidermal Growth Factor Receptors Clin. Cancer Res., July 1, 2005; 11(13): 4923 - 4933. [Abstract] [Full Text] [PDF] |
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T. Szoke, K. Kayser, J.-D. Baumhakel, I. Trojan, J. Furak, L. Tiszlavicz, J. Eller, and K. Boda Prognostic significance of microvascularization in cases of operated lung cancer Eur. J. Cardiothorac. Surg., June 1, 2005; 27(6): 1106 - 1111. [Abstract] [Full Text] [PDF] |
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L. S. Rosen VEGF-Targeted Therapy: Therapeutic Potential and Recent Advances Oncologist, June 1, 2005; 10(6): 382 - 391. [Abstract] [Full Text] [PDF] |
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R. S. Herbst, A. Onn, and A. Sandler Angiogenesis and Lung Cancer: Prognostic and Therapeutic Implications J. Clin. Oncol., May 10, 2005; 23(14): 3243 - 3256. [Abstract] [Full Text] [PDF] |
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K. D. Miller, J. M. Trigo, C. Wheeler, A. Barge, J. Rowbottom, G. Sledge, and J. Baselga A Multicenter Phase II Trial of ZD6474, a Vascular Endothelial Growth Factor Receptor-2 and Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients with Previously Treated Metastatic Breast Cancer Clin. Cancer Res., May 1, 2005; 11(9): 3369 - 3376. [Abstract] [Full Text] [PDF] |
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X.-F. Zhu, B.-F. Xie, J.-M. Zhou, G.-K. Feng, Z.-C. Liu, X.-Y. Wei, F.-X. Zhang, M.-F. Liu, and Y.-X. Zeng Blockade of Vascular Endothelial Growth Factor Receptor Signal Pathway and Antitumor Activity of ON-III (2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone), a Component from Chinese Herbal Medicine Mol. Pharmacol., May 1, 2005; 67(5): 1444 - 1450. [Abstract] [Full Text] [PDF] |
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W.-T. Chen, C.-J. Huang, M.-T. Wu, S.-F. Yang, Y.-C. Su, and C.-Y. Chai Hypoxia-inducible Factor-1{alpha} is Associated with Risk of Aggressive Behavior and Tumor Angiogenesis in Gastrointestinal Stromal Tumor Jpn. J. Clin. Oncol., April 1, 2005; 35(4): 207 - 213. [Abstract] [Full Text] [PDF] |
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S. Arora, J. Kaur, C. Sharma, M. Mathur, S. Bahadur, N. K. Shukla, S. V.S. Deo, and R. Ralhan Stromelysin 3, Ets-1, and Vascular Endothelial Growth Factor Expression in Oral Precancerous and Cancerous Lesions: Correlation with Microvessel Density, Progression, and Prognosis Clin. Cancer Res., March 15, 2005; 11(6): 2272 - 2284. [Abstract] [Full Text] [PDF] |
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S. Dalal, A. M. Berry, C. J. Cullinane, D. C. Mangham, R. Grimer, I. J. Lewis, C. Johnston, V. Laurence, and S. A. Burchill Vascular Endothelial Growth Factor: A Therapeutic Target for Tumors of the Ewing's Sarcoma Family Clin. Cancer Res., March 15, 2005; 11(6): 2364 - 2378. [Abstract] [Full Text] [PDF] |
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W. Gong, L. Wang, J. C. Yao, J. A. Ajani, D. Wei, K. D. Aldape, K. Xie, R. Sawaya, and S. Huang Expression of Activated Signal Transducer and Activator of Transcription 3 Predicts Expression of Vascular Endothelial Growth Factor in and Angiogenic Phenotype of Human Gastric Cancer Clin. Cancer Res., February 15, 2005; 11(4): 1386 - 1393. [Abstract] [Full Text] [PDF] |
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D. J. Hicklin and L. M. Ellis Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis J. Clin. Oncol., February 10, 2005; 23(5): 1011 - 1027. [Abstract] [Full Text] [PDF] |
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K. D. Miller, L. I. Chap, F. A. Holmes, M. A. Cobleigh, P. K. Marcom, L. Fehrenbacher, M. Dickler, B. A. Overmoyer, J. D. Reimann, A. P. Sing, et al. Randomized Phase III Trial of Capecitabine Compared With Bevacizumab Plus Capecitabine in Patients With Previously Treated Metastatic Breast Cancer J. Clin. Oncol., February 1, 2005; 23(4): 792 - 799. [Abstract] [Full Text] [PDF] |
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S A Borg, K E Kerry, J A Royds, R D Battersby, and T H Jones Correlation of VEGF production with IL1{alpha} and IL6 secretion by human pituitary adenoma cells Eur. J. Endocrinol., February 1, 2005; 152(2): 293 - 300. [Abstract] [Full Text] [PDF] |
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M. Popkov, N. Jendreyko, D. B. McGavern, C. Rader, and C. F. Barbas III Targeting Tumor Angiogenesis with Adenovirus-Delivered Anti-Tie-2 Intrabody Cancer Res., February 1, 2005; 65(3): 972 - 981. [Abstract] [Full Text] [PDF] |
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M. Fujita, I. Hayashi, S. Yamashina, A. Fukamizu, M. Itoman, and M. Majima Angiotensin type 1a receptor signaling-dependent induction of vascular endothelial growth factor in stroma is relevant to tumor-associated angiogenesis and tumor growth Carcinogenesis, February 1, 2005; 26(2): 271 - 279. [Abstract] [Full Text] [PDF] |
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S. Rehman and G. C. Jayson Molecular Imaging of Antiangiogenic Agents Oncologist, February 1, 2005; 10(2): 92 - 103. [Abstract] [Full Text] [PDF] |
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A. Koster, J. H.J.M. van Krieken, M. A. MacKenzie, M. Schraders, G. F. Borm, J. A.W.M. van der Laak, W. Leenders, K. Hebeda, and J. M.M. Raemaekers Increased Vascularization Predicts Favorable Outcome in Follicular Lymphoma Clin. Cancer Res., January 1, 2005; 11(1): 154 - 161. [Abstract] [Full Text] [PDF] |
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M.-H. Li, Z.-H. Miao, W.-F. Tan, J.-M. Yue, C. Zhang, L.-P. Lin, X.-W. Zhang, and J. Ding Pseudolaric Acid B Inhibits Angiogenesis and Reduces Hypoxia-Inducible Factor 1{alpha} by Promoting Proteasome-Mediated Degradation Clin. Cancer Res., December 15, 2004; 10(24): 8266 - 8274. [Abstract] [Full Text] [PDF] |
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T Yanagawa, T Funasaka, S Tsutsumi, H Watanabe, and A Raz Novel roles of the autocrine motility factor/phosphoglucose isomerase in tumor malignancy Endocr. Relat. Cancer, December 1, 2004; 11(4): 749 - 759. [Abstract] [Full Text] [PDF] |
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S. Hoffmann, L. C. Hofbauer, V. Scharrenbach, A. Wunderlich, I. Hassan, S. Lingelbach, and A. Zielke Thyrotropin (TSH)-Induced Production of Vascular Endothelial Growth Factor in Thyroid Cancer Cells in Vitro: Evaluation of TSH Signal Transduction and of Angiogenesis-Stimulating Growth Factors J. Clin. Endocrinol. Metab., December 1, 2004; 89(12): 6139 - 6145. [Abstract] [Full Text] [PDF] |
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Y. Takemoto, H. Yano, S. Momosaki, S. Ogasawara, N. Nishida, S. Kojiro, T. Kamura, and M. Kojiro Antiproliferative Effects of Interferon-{alpha}Con1 on Ovarian Clear Cell Adenocarcinoma In vitro and In vivo Clin. Cancer Res., November 1, 2004; 10(21): 7418 - 7426. [Abstract] [Full Text] [PDF] |
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P. Vaupel The Role of Hypoxia-Induced Factors in Tumor Progression Oncologist, November 1, 2004; 9(suppl_5): 10 - 17. [Abstract] [Full Text] [PDF] |
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