Skip Navigation

JNCI Journal of the National Cancer Institute 1991 83(16):1142-1148; doi:10.1093/jnci/83.16.1142
© 1991 by Oxford University Press
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Shopland, D. R.
Right arrow Articles by Peachacek, T. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shopland, D. R.
Right arrow Articles by Peachacek, T. F.
Social Bookmarking
 Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of the National Cancer Institute, Vol. 83, No. 16, 1142-1148, August 21, 1991
© 1991 Oxford University Press

Smoking-Attributable Cancer Mortality in 1991: Is Lung Cancer Now the Leading Cause of Death Among Smokers in the United States?

Donald R. Shopland*, Harmon J. Eyre, Terry F. Peachacek

Smoking and Tobacco Control Program, Division of Cancer Prevention and Control, National Cancer Institute Bethesda, Md.
American Cancer Society Atlanta, Ga.

*Correspondence to: Donald R. Shopland. Smoking and Tobacco Control jProgram, Executive Plaza North, Rm. 241, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892.

Finding from the new American Cancer Society prospective study of 1.2 million men and women indicate that mortality risks among smokers have increased substantially for most of the eight major cancer sites causally associated with cigarette smoking. Lung cancer risk for male smokers doubled, while the risk for females increased more than fourfold. On the basis of the new American Cancer Society relative risks, we project that cigarette smoking alone will contribute to slightly more than 157 000 of the 514 000 total cancer deaths expected to occur in the United States in 1991. Overall, smoking directly contributes to 21.5% of all cancer deaths in women but 45% of all cancer deaths in men. It would also appear that lung cancer has now displaced cornary heart disease as the single leading cause of excess mortality among smokers in the United States. [J Natl Cancer Inst 83:1142–1148, 1991]



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
JNCI J Natl Cancer InstHome page
M. R. Spitz, W. K. Hong, C. I. Amos, X. Wu, M. B. Schabath, Q. Dong, S. Shete, and C. J. Etzel
A Risk Model for Prediction of Lung Cancer
J Natl Cancer Inst, May 2, 2007; 99(9): 715 - 726.
[Abstract] [Full Text] [PDF]


Home page
CarcinogenesisHome page
K. El-Bayoumy, A. Das, B. Narayanan, N. Narayanan, E. S. Fiala, D. Desai, C. V. Rao, S. Amin, and R. Sinha
Molecular targets of the chemopreventive agent 1,4-phenylenebis (methylene)-selenocyanate in human non-small cell lung cancer
Carcinogenesis, July 1, 2006; 27(7): 1369 - 1376.
[Abstract] [Full Text] [PDF]


Home page
JNCI J Natl Cancer InstHome page
M. J. Thun, S. J. Henley, D. Burns, A. Jemal, T. G. Shanks, and E. E. Calle
Lung cancer death rates in lifelong nonsmokers.
J Natl Cancer Inst, May 17, 2006; 98(10): 691 - 699.
[Abstract] [Full Text] [PDF]


Home page
Cancer Res.Home page
Y.-L. Zheng, C. A. Loffredo, A. J. Alberg, Z. Yu, R. T. Jones, D. Perlmutter, L. Enewold, M. J. Krasna, R. Yung, P. G. Shields, et al.
Less Efficient G2-M Checkpoint Is Associated with an Increased Risk of Lung Cancer in African Americans
Cancer Res., October 15, 2005; 65(20): 9566 - 9573.
[Abstract] [Full Text] [PDF]


Home page
Ann OncolHome page
J. Hu, C. Galeone, R. Lui, C. Pelucchi, C. L. Vecchia, and E. Negri
Smoking and lung cancer in Harbin, northeast China
Ann. Onc., October 1, 2005; 16(10): 1605 - 1608.
[Abstract] [Full Text] [PDF]


Home page
Clin. Cancer Res.Home page
Y. Hu, M. P. McDermott, and S. A. Ahrendt
The p53 Codon 72 Proline Allele Is Associated with p53 Gene Mutations in Non-Small Cell Lung Cancer
Clin. Cancer Res., April 1, 2005; 11(7): 2502 - 2509.
[Abstract] [Full Text] [PDF]


Home page
Cancer Epidemiol. Biomarkers Prev.Home page
W.-M. Gao, M. Romkes, J. M. Siegfried, J. D. Luketich, and P. Keohavong
No Association between the XPD 312, 751, or XRCC1 399 Polymorphisms and K-ras Gene Mutation in Smoking Non-Small-Cell Lung Cancer
Cancer Epidemiol. Biomarkers Prev., April 1, 2004; 13(4): 673 - 675.
[Full Text] [PDF]


Home page
Cancer Epidemiol. Biomarkers Prev.Home page
M. R. Spitz, Q. Wei, Q. Dong, C. I. Amos, and X. Wu
Genetic Susceptibility to Lung Cancer: The Role of DNA Damage and Repair
Cancer Epidemiol. Biomarkers Prev., August 1, 2003; 12(8): 689 - 698.
[Full Text] [PDF]


Home page
Cancer Epidemiol. Biomarkers Prev.Home page
P. P. Medina, S. A. Ahrendt, M. Pollan, P. Fernandez, D. Sidransky, and M. Sanchez-Cespedes
Screening of Homologous Recombination Gene Polymorphisms in Lung Cancer Patients Reveals an Association of the NBS1-185Gln Variant and p53 Gene Mutations
Cancer Epidemiol. Biomarkers Prev., August 1, 2003; 12(8): 699 - 704.
[Abstract] [Full Text] [PDF]


Home page
JNCI J Natl Cancer InstHome page
S. A. Ahrendt, Y. Hu, M. Buta, M. P. McDermott, N. Benoit, S. C. Yang, L. Wu, and D. Sidransky
p53 Mutations and Survival in Stage I Non-Small-Cell Lung Cancer: Results of a Prospective Study
J Natl Cancer Inst, July 2, 2003; 95(13): 961 - 970.
[Abstract] [Full Text] [PDF]


Home page
JCOHome page
D. Ratschiller, J. Heighway, M. Gugger, A. Kappeler, F. Pirnia, R.A. Schmid, M.M. Borner, and D.C. Betticher
Cyclin D1 Overexpression in Bronchial Epithelia of Patients With Lung Cancer Is Associated With Smoking and Predicts Survival
J. Clin. Oncol., June 1, 2003; 21(11): 2085 - 2093.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
E. B. Lee, T. I. Park, S. H. Park, and J. Y. Park
Loss of heterozygosity on the long arm of chromosome 21 in non-small cell lung cancer
Ann. Thorac. Surg., May 1, 2003; 75(5): 1597 - 1600.
[Abstract] [Full Text] [PDF]


Home page
CarcinogenesisHome page
Y.-L. Zheng, C. A. Loffredo, Z. Yu, R. T. Jones, M. J. Krasna, A. J. Alberg, R. Yung, D. Perlmutter, L. Enewold, C. C. Harris, et al.
Bleomycin-induced chromosome breaks as a risk marker for lung cancer: a case-control study with population and hospital controls
Carcinogenesis, February 1, 2003; 24(2): 269 - 274.
[Abstract] [Full Text] [PDF]


Home page
Int J EpidemiolHome page
A. Barchielli and D. Balzi
Nine-year follow-up of a survey on smoking habits in Florence (Italy): higher mortality among non-responders
Int. J. Epidemiol., October 1, 2002; 31(5): 1038 - 1042.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Respir. Cell Mol. Bio.Home page
A. K. Greenberg, S. Basu, J. Hu, T.-a. Yie, K. M. Tchou-Wong, W. N. Rom, and T. C. Lee
Selective p38 Activation in Human Non-Small Cell Lung Cancer
Am. J. Respir. Cell Mol. Biol., May 1, 2002; 26(5): 558 - 564.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
S. Houterman, H.C. Boshuizen, W.M.M. Verschuren, S. Giampaoli, A. Nissinen, A. Menotti, and D. Kromhout
Predicting cardiovascular risk in the elderly in different European countries
Eur. Heart J., February 2, 2002; 23(4): 294 - 300.
[Abstract] [Full Text] [PDF]


Home page
JNCI J Natl Cancer InstHome page
N. L. Benowitz, E. J. Perez-Stable, B. Herrera, and P. Jacob III
Slower Metabolism and Reduced Intake of Nicotine From Cigarette Smoking in Chinese-Americans
J Natl Cancer Inst, January 16, 2002; 94(2): 108 - 115.
[Abstract] [Full Text] [PDF]


Home page
Genes Dev.Home page
G. H. Fisher, S. L. Wellen, D. Klimstra, J. M. Lenczowski, J. W. Tichelaar, M. J. Lizak, J. A. Whitsett, A. Koretsky, and H. E. Varmus
Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes
Genes & Dev., December 15, 2001; 15(24): 3249 - 3262.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Respir. Crit. Care Med.Home page
T. L. FEENSTRA, M. L. L. van GENUGTEN, R. T. HOOGENVEEN, E. F. WOUTERS, and M. P. M. H. RUTTEN-van MOLKEN
The Impact of Aging and Smoking on the Future Burden of Chronic Obstructive Pulmonary Disease . A Model Analysis in the Netherlands
Am. J. Respir. Crit. Care Med., August 15, 2001; 164(4): 590 - 596.
[Abstract] [Full Text] [PDF]


Home page
Cancer Epidemiol. Biomarkers Prev.Home page
J.-M. Yuan, R. K. Ross, X.-D. Chu, Y.-T. Gao, and M. C. Yu
Prediagnostic Levels of Serum {beta}-Cryptoxanthin and Retinol Predict Smoking-related Lung Cancer Risk in Shanghai, China
Cancer Epidemiol. Biomarkers Prev., July 1, 2001; 10(7): 767 - 773.
[Abstract] [Full Text] [PDF]


Home page
Cancer Res.Home page
M. Sanchez-Cespedes, P. A. Decker, K. M. Doffek, M. Esteller, W. H. Westra, E. A. Alawi, J. G. Herman, M. J. Demeure, D. Sidransky, and S. A. Ahrendt
Increased Loss of Chromosome 9p21 but not p16 Inactivation in Primary Non-Small Cell Lung Cancer from Smokers
Cancer Res., March 1, 2001; 61(5): 2092 - 2096.
[Abstract] [Full Text]


Home page
JNCI J Natl Cancer InstHome page
D. Feskanich, R. G. Ziegler, D. S. Michaud, E. L. Giovannucci, F. E. Speizer, W. C. Willett, and G. A. Colditz
Prospective Study of Fruit and Vegetable Consumption and Risk of Lung Cancer Among Men and Women
J Natl Cancer Inst, November 15, 2000; 92(22): 1812 - 1823.
[Abstract] [Full Text] [PDF]


Home page
CarcinogenesisHome page
A. A.W. TenHave-Opbroek, X.-B. Shi, and P. H. Gumerlock
3-Methylcholanthrene triggers the differentiation of alveolar tumor cells from canine bronchial basal cells and an altered p53 gene promotes their clonal expansion
Carcinogenesis, August 1, 2000; 21(8): 1477 - 1484.
[Abstract] [Full Text] [PDF]


Home page
CarcinogenesisHome page
L. Cheng, M. R. Spitz, W. K. Hong, and Q. Wei
Reduced expression levels of nucleotide excision repair genes in lung cancer: a case-control analysis
Carcinogenesis, August 1, 2000; 21(8): 1527 - 1530.
[Abstract] [Full Text] [PDF]


Home page
Cancer Res.Home page
S. A. Ahrendt, J. T. Chow, S. C. Yang, L. Wu, M.-J. Zhang, J. Jen, and D. Sidransky
Alcohol Consumption and Cigarette Smoking Increase the Frequency of p53 Mutations in Non-Small Cell Lung Cancer
Cancer Res., June 1, 2000; 60(12): 3155 - 3159.
[Abstract] [Full Text]


Home page
JCOHome page
J. Ayoub, R. Jean-Francois, Y. Cormier, D. Meyer, Y. Ying, P. Major, C. Desjardins, and W.E.C. Bradley
Placebo-Controlled Trial of 13-cis-Retinoic Acid Activity on Retinoic Acid Receptor-Beta Expression in a Population at High Risk: Implications for Chemoprevention of Lung Cancer
J. Clin. Oncol., November 1, 1999; 17(11): 3546 - 3552.
[Abstract] [Full Text] [PDF]


Home page
JNCI J Natl Cancer InstHome page
A. W. Bergen and N. Caporaso
Cigarette Smoking
J Natl Cancer Inst, August 18, 1999; 91(16): 1365 - 1375.
[Abstract] [Full Text] [PDF]


Home page
Arch Intern MedHome page
D. R. Jacobs Jr, H. Adachi, I. Mulder, D. Kromhout, A. Menotti, A. Nissinen, H. Blackburn, and for the Seven Countries Study Group
Cigarette Smoking and Mortality Risk: Twenty-five-Year Follow-up of the Seven Countries Study
Arch Intern Med, April 12, 1999; 159(7): 733 - 740.
[Abstract] [Full Text] [PDF]


Home page
Indoor and Built EnvironmentHome page
J. B. L. Gee
Smoking and Occupational Lung Disease Epidemiology
Indoor and Built Environment, March 1, 1999; 8(2): 132 - 135.
[Abstract] [PDF]


Home page
BMJHome page
P. Lee, G. Scherer, W.-D. Heller, F. Nyberg, G. Pershagen, A K Hackshaw, M R Law, and N J Wald
Passive smoking and lung cancer
BMJ, August 1, 1998; 317(7154): 346 - 346.
[Full Text]


Home page
Stat Methods Med ResHome page
A K Hackshaw
Lung cancer and passive smoking
Statistical Methods in Medical Research, April 1, 1998; 7(2): 119 - 136.
[Abstract] [PDF]


Home page
JAMAHome page
C. Zheng-Ming, Z. Xu, R. Collins, W.-X. Li, and R. Peto
Early Health Effects of the Emerging Tobacco Epidemic in China: A 16-Year Prospective Study
JAMA, November 12, 1997; 278(18): 1500 - 1504.
[Abstract] [PDF]


Home page
JAMAHome page
J.-M. Yuan, R. K. Ross, X.-L. Wang, Y.-T. Gao, B. E. Henderson, and M. C. Yu
Morbidity and Mortality in Relation to Cigarette Smoking in Shanghai, China: A Prospective Male Cohort Study
JAMA, June 5, 1996; 275(21): 1646 - 1650.
[Abstract] [PDF]


Home page
Arch Fam MedHome page
T. P. Houston
Smoking Cessation: Putting Prevention Into Practice
Arch Fam Med, September 1, 1992; 1(1): 128 - 135.
[Abstract] [PDF]


Home page
RadiologyHome page
S. Diederich, D. Wormanns, M. Semik, M. Thomas, H. Lenzen, N. Roos, and W. Heindel
Screening for Early Lung Cancer with Low-Dose Spiral CT: Prevalence in 817 Asymptomatic Smokers
Radiology, March 1, 2002; 222(3): 773 - 781.
[Abstract] [Full Text] [PDF]



Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.