Environmental Factors and High Risk of Esophageal Cancer Among Men in Coastal South Carolina

doi:10.1093/jnci/80.20.1620

JNCI Journal of the National Cancer Institute 1988 80(20):1620-1625; doi:10.1093/jnci/80.20.1620
© 1988 by Oxford University Press

This Article

	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Add to My Personal Archive
	Download to citation manager
	Request Permissions

Google Scholar

	Articles by Brown, L. M.
	Articles by Fraumeni, J. F.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Brown, L. M.
	Articles by Fraumeni, J. F., Jr.

Social Bookmarking

	What's this?

Journal of the National Cancer Institute, Vol. 80, No. 20, 1620-1625, December 21, 1988
© 1988 Oxford University Press

Environmental Factors and High Risk of Esophageal Cancer Among Men in Coastal South Carolina

Linda Morris Brown^*, William J. Blot, Stanley H. Schuman, Vara M. Smith, Abby G. Ershow, Richard D. Marks, Joseph F. Fraumeni, Jr.

Epidemiology and Biostatistics Program, Division of Cancer Etiology, National Cancer Institute Bethesda, MD
Medical University of South Carolina Charleston, SC

^*Correspondence to: Linda Morris Brown, Executive Plaza North, Rm 415, National Institutes of Health, Bethesda, MD 20892.

A case-control study involving interviews of 207 men with esophagealcancer and 422 control subjects or their next of kin was conductedto identify reasons for the unusually high rates of esophagealcancer among men in coastal South Carolina. Tobacco and alcohol,including moonshine, were identified as the major determinantsof esophageal cancer risk. Increased risk was also associatedwith low intake of fresh fruits but not with drinking of localherbal teas. The findings suggest that efforts aimed at reducingtobacco and alcohol use will help to lower the elevated ratesof esophageal cancer in coastal South Carolina.

CiteULike

Connotea

Del.icio.us What's this?

This article has been cited by other articles:

W. Garavello, E. Negri, R. Talamini, F. Levi, P. Zambon, L. Dal Maso, C. Bosetti, S. Franceschi, and C. La Vecchia
Family History of Cancer, Its Combination with Smoking and Drinking, and Risk of Squamous Cell Carcinoma of the Esophagus
Cancer Epidemiol. Biomarkers Prev., June 1, 2005; 14(6): 1390 - 1393.
[Abstract] [Full Text] [PDF]

E. Riboli and T. Norat
Epidemiologic evidence of the protective effect of fruit and vegetables on cancer risk
Am. J. Clinical Nutrition, September 1, 2003; 78(3): 559S - 569.
[Abstract] [Full Text] [PDF]

E.-S. Hwang and P. E. Bowen
Can the Consumption of Tomatoes or Lycopene Reduce Cancer Risk?
Integr Cancer Ther, June 1, 2002; 1(2): 121 - 132.
[Abstract] [PDF]

S. Mizobuchi, M. Furihata, H. Sonobe, Y. Ohtsuki, T. Ishikawa, H. Murakami, A. Kurabayashi, S. Ogoshi, and S. Sasaguri
Association Between p53 Immunostaining and Cigarette Smoking in Squamous Cell Carcinoma of the Esophagus
Jpn. J. Clin. Oncol., October 1, 2000; 30(10): 423 - 428.
[Abstract] [Full Text] [PDF]

J. Lagergren, W. Ye, A. Lindgren, and O. Nyrén
Heredity and Risk of Cancer of the Esophagus and Gastric Cardia
Cancer Epidemiol. Biomarkers Prev., July 1, 2000; 9(7): 757 - 760.
[Abstract] [Full Text]

G. Launoy, C. Milan, J. Faivre, P. Pienkowski, and M. Gignoux
Tobacco type and risk of squamous cell cancer of the oesophagus in males: a French multicentre case-control study
Int. J. Epidemiol., February 1, 2000; 29(1): 36 - 42.
[Abstract] [Full Text] [PDF]

E. Giovannucci
Tomatoes, Tomato-Based Products, Lycopene, and Cancer: Review of the Epidemiologic Literature
J Natl Cancer Inst, February 17, 1999; 91(4): 317 - 331.
[Abstract] [Full Text] [PDF]

C. E. Gates, C. E. Reed, J. S. Bromberg, E. T. Everett, P. L. Baron, and S. b. F. A. Crawford Jr.
Prevalence of p53 mutations in patients with squamous cell carcinoma of the esophagus
J. Thorac. Cardiovasc. Surg., July 1, 1994; 108(1): 148 - 152.
[Abstract] [Full Text]

				E. Riboli and T. Norat Epidemiologic evidence of the protective effect of fruit and vegetables on cancer risk Am. J. Clinical Nutrition, September 1, 2003; 78(3): 559S - 569. [Abstract] [Full Text] [PDF]

				E.-S. Hwang and P. E. Bowen Can the Consumption of Tomatoes or Lycopene Reduce Cancer Risk? Integr Cancer Ther, June 1, 2002; 1(2): 121 - 132. [Abstract] [PDF]

				S. Mizobuchi, M. Furihata, H. Sonobe, Y. Ohtsuki, T. Ishikawa, H. Murakami, A. Kurabayashi, S. Ogoshi, and S. Sasaguri Association Between p53 Immunostaining and Cigarette Smoking in Squamous Cell Carcinoma of the Esophagus Jpn. J. Clin. Oncol., October 1, 2000; 30(10): 423 - 428. [Abstract] [Full Text] [PDF]

				J. Lagergren, W. Ye, A. Lindgren, and O. Nyrén Heredity and Risk of Cancer of the Esophagus and Gastric Cardia Cancer Epidemiol. Biomarkers Prev., July 1, 2000; 9(7): 757 - 760. [Abstract] [Full Text]

				G. Launoy, C. Milan, J. Faivre, P. Pienkowski, and M. Gignoux Tobacco type and risk of squamous cell cancer of the oesophagus in males: a French multicentre case-control study Int. J. Epidemiol., February 1, 2000; 29(1): 36 - 42. [Abstract] [Full Text] [PDF]

				E. Giovannucci Tomatoes, Tomato-Based Products, Lycopene, and Cancer: Review of the Epidemiologic Literature J Natl Cancer Inst, February 17, 1999; 91(4): 317 - 331. [Abstract] [Full Text] [PDF]

				C. E. Gates, C. E. Reed, J. S. Bromberg, E. T. Everett, P. L. Baron, and S. b. F. A. Crawford Jr. Prevalence of p53 mutations in patients with squamous cell carcinoma of the esophagus J. Thorac. Cardiovasc. Surg., July 1, 1994; 108(1): 148 - 152. [Abstract] [Full Text]